ReviewNutrients2021
Multinutrient Biofortification of Maize (
Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed.
- Spatial Distribution of Inadequate Apparent Intake of Protein, Lysine, and Tryptophan among Malawi's Households with Children Aged <5 y: Evidence from the 2019-2020 Integrated Household Survey.Current developments in nutrition · 2026Article
- Maize Biofortification Approaches for Fighting Malnutrition in Sub-Saharan Africa.Plant-environment interactions (Hoboken, N.J.) · 2026Review
- Introgression of QTL hotspot regions enhances grain yield and maize lethal necrosis resistance in elite maize lines.Scientific reports · 2026Article
- Prevalence of protein, lysine, and tryptophan inadequacy and their relation to stunting among Malawian under five children: evidence from the 2019/20 Integrated Household Survey.Frontiers in nutrition · 2026Article
- Early Sowing Approach for Developing Climate Resilient Maize: Cold Stress Impact on Germination of Adapted Inbred Lines with High Nutritive Value.Plants (Basel, Switzerland) · 2025Article
- Resilience of Maize to Environmental Stress: Insights into Drought and Heat Tolerance.International journal of molecular sciences · 2025Review
- Optimization of Nutritional and Sensory Properties of Unleavened Flatbread Developed From Maize-Boiled Rhizome of Water Lily-Fish.Food science & nutrition · 2025Article
- Nutritional composition ofOpen research Africa · 2025Review
- Biofortification of baby corn: Integrating agronomic and genetic approaches to address zinc micronutrient deficiencies - global perspectives and future challenges.Frontiers in plant science · 2025Review
- The current status of genetic biofortification in alleviating malnutrition in Africa.Journal, genetic engineering & biotechnology · 2024Review
- Developing an Acceptable Nixtamalised Maize Product for South African Consumers: Sensory, Survey and Nutrient Analysis.Foods (Basel, Switzerland) · 2024Article
- Maize Grain Metabolite Profiling by NMR: Effects of Growing Year, Variety, and Cropping System.Molecules (Basel, Switzerland) · 2024Article
- Linkage mapping and genomic prediction of grain quality traits in tropical maize (Frontiers in genetics · 2024Article
- Accelerated shelf life determination of corn snack bars.Italian journal of food safety · 2023Article
- Increasing aleurone layer number and pericarp yield for elevated nutrient content in maize.G3 (Bethesda, Md.) · 2023Article
- Genotype by Environment Interaction in Grain Iron and Zinc Concentration and Yield of Maize Hybrids under Low Nitrogen and Optimal Conditions.Plants (Basel, Switzerland) · 2023Article
- Biofortification: an approach to eradicate micronutrient deficiency.Frontiers in nutrition · 2023Review
- Combining ability and testcross performance of multi-nutrient maize under stress and non-stress environments.Frontiers in plant science · 2023Article
- Impact of CGIAR maize germplasm in Sub-Saharan Africa.Field crops research · 2023Article
- Genotypic and environmental effects on quality and nutritional attributes of Moroccan barley cultivars and elite breeding lines.Frontiers in nutrition · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Macro and micronutrient deficiencies pose serious health challenges globally, with the largest impact in developing regions such as subSaharan Africa (SSA), Latin America and South Asia. Maize is a good source of calories but contains low concentrations of essential nutrients. Major limiting nutrients in maize-based diets are essential amino acids such as lysine and tryptophan, and micronutrients such as vitamin A, zinc (Zn) and iron (Fe). Responding to these challenges, separate maize biofortification programs have been designed worldwide, resulting in several cultivars with high levels of provitamin A, lysine, tryptophan, Zn and Fe being commercialized. This strategy of developing single-nutrient biofortified cultivars does not address the nutrient deficiency challenges in SSA in an integrated manner. Hence, development of maize with multinutritional attributes can be a sustainable and cost-effective strategy for addressing the problem of nutrient deficiencies in SSA. This review provides a synopsis of the health challenges associated with Zn, provitamin A and tryptophan deficiencies and link these to vulnerable societies; a synthesis of past and present intervention measures for addressing nutrient deficiencies in SSA; and a discussion on the possibility of developing maize with multinutritional quality attributes, but also with adaptation to stress conditions in SSA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.