Evidence map›Paper›PMID 33807031›Full record

ReviewMicromachines2021

Optical Detection Methods for High-Throughput Fluorescent Droplet Microflow Cytometry.

Kaiser Pärnamets, Tamas Pardy, Ants Koel, Toomas Rang, Ott Scheler, Yannick Le Moullec, Fariha Afrin

Open access · goldAbstract readReview
In one paragraph

Review in Micromachines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kaiser PärnametsThomas Johann Seebeck Department of Electronics, Tallinn University of Technology, 19086 Tallinn, Estonia.ORCID 0000-0001-7563-2449
Tamas PardyDepartment of Chemistry and Biotechnology, Tallinn University of Technology, 19086 Tallinn, Estonia.ORCID 0000-0003-1360-4201
Ants KoelThomas Johann Seebeck Department of Electronics, Tallinn University of Technology, 19086 Tallinn, Estonia.ORCID 0000-0001-5635-0139
Toomas RangThomas Johann Seebeck Department of Electronics, Tallinn University of Technology, 19086 Tallinn, Estonia.
Ott SchelerDepartment of Chemistry and Biotechnology, Tallinn University of Technology, 19086 Tallinn, Estonia.ORCID 0000-0002-8428-1350
Yannick Le MoullecThomas Johann Seebeck Department of Electronics, Tallinn University of Technology, 19086 Tallinn, Estonia.ORCID 0000-0003-4667-621X
Fariha AfrinThomas Johann Seebeck Department of Electronics, Tallinn University of Technology, 19086 Tallinn, Estonia.ORCID 0000-0001-9970-7003
Tallinn University of Technology · EE

Funding

Eesti Teadusagentuur IUT1911Eesti Teadusagentuur MOBTP109Eesti Teadusagentuur PRG620Eesti Teadusagentuur PUT1435Horizon 2020 668995IT tippkeskus EXCITE TAR16013
6 · The paper itself

Abstract

High-throughput microflow cytometry has become a focal point of research in recent years. In particular, droplet microflow cytometry (DMFC) enables the analysis of cells reacting to different stimuli in chemical isolation due to each droplet acting as an isolated microreactor. Furthermore, at high flow rates, the droplets allow massive parallelization, further increasing the throughput of droplets. However, this novel methodology poses unique challenges related to commonly used fluorometry and fluorescent microscopy techniques. We review the optical sensor technology and light sources applicable to DMFC, as well as analyze the challenges and advantages of each option, primarily focusing on electronics. An analysis of low-cost and/or sufficiently compact systems that can be incorporated into portable devices is also presented.

Indexed as

droplet microfluidicslight sourcesmicroflow cytometryoptical sensors

Identifiers

PMID33807031
PMCPMC8004903
OpenAlexW3138480849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.