ReviewPlants (Basel, Switzerland)2021
A Review on Epidemiological and Clinical Studies on Buckwheat Allergy.
Review in Plants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Update on occupational contact urticaria: a systematic narrative review.Current opinion in allergy and clinical immunology · 2026Pooled it
- Systematic Review of Human and Animal Evidence on the Role of Buckwheat Consumption on Gastrointestinal Health.Nutrients · 2022Pooled it
- Buckwheat Husk: An Underexplored Source of Bioactive Compounds and Functional Food Applications.Foods (Basel, Switzerland) · 2026Review
- Dietary Adjuvanticity in the Modern Plant Exposome: Implications for Immune-Mediated Inflammatory Diseases.Nutrients · 2026Review
- Food-induced anaphylaxis to plant allergens in adolescents and adults: Data from the allergy Vigilance Network (2002-2024).The World Allergy Organization journal · 2026Article
- Clinical characteristics and IgE-binding protein profiles of patients with buckwheat allergy in China.The World Allergy Organization journal · 2026Article
- A Narrative Review on Pseudocereals and Cardiometabolic Health: Biological Mechanisms and Evidence from Human Studies.Nutrients · 2026Review
- Distribution of photosensitive fagopyrin in buckwheat flowers and its potential biological relevance.Scientific reports · 2025Article
- Early Origins of Asthma and Allergies: Clues From Studies in China.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025Review
- [Food allergy as occupational disease].Dermatologie (Heidelberg, Germany) · 2025Review
- Buckwheat: An Underutilized Himalayan Crop with Multifaceted Nutraceutical Benefits.Recent advances in food, nutrition & agriculture · 2025Review
- Occupational buckwheat allergy in a health food store employee: From inhalative exposure to anaphylaxis.Allergologie select · 2025Article
- Article
- Anaphylactic Shock Caused by Eating Buckwheat.Journal of clinical medicine · 2024Article
- Botanical Impurities in the Supply Chain: A New Allergenic Risk Exacerbated by Geopolitical Challenges.Nutrients · 2024Review
- Early Introduction of Novel and Less-Studied Food Allergens in the Plant-Based Era: Considerations for US and EU Infant Formula Regulations.Nutrients · 2023Review
- Characterization of 2S albumin allergenic proteins for anaphylaxis in common buckwheat.Food chemistry. Molecular sciences · 2022Article
- Phytochemistry, Bioactivities of Metabolites, and Traditional Uses ofMolecules (Basel, Switzerland) · 2022Review
- Buckwheat and Amaranth as Raw Materials for Brewing, a Review.Plants (Basel, Switzerland) · 2022Review
- Wheat supplement with buckwheat affect gut microbiome composition and circulate short-chain fatty acids.Frontiers in nutrition · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCultivated buckwheat include two species originating from China: common buckwheat (
methodsA search on buckwheat allergy in the medical datbase PubMed from 1970-2020.
resultA number of allergenic proteins have been identified in common buckwheat (e.g., Fag e 1, Fag e 2 and Fag e 3) and in tartary buckwheat (e.g., Fag t 1, Fag t 2, Fag t 3). Clinically relevant cross-reactivity has been described between buckwheat and peanut, latex, coconut, quinoa, and poppy seed. The prevalence of buckwheat allergy in the population can be estimated as 0.1-0.4% in Japan, Korea and buckwheat consuming areas of China. Among patients in allergy clinics in different countries, 2-7% has confirmed buckwheat allergy. School studies from Japan and Korea found 4-60 cases of buckwheat-related anaphylaxis per 100,000 school children. The incidence of severe allergic reactions to buckwheat, including anaphylaxis, can be estimated as 0.1-0.01 cases per 100,000 person-years.
conclusionsBuckwheat allergy is a neglected allegy deserving further attention but severe allergic reactions are rare.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.