Evidence map›Paper›PMID 33806868›Full record

ArticleCancers2021

The Epithelial-Mesenchymal Transcription Factor

Hanmin Wang, Evgeny Chirshev, Nozomi Hojo, Tise Suzuki, Antonella Bertucci, Michael Pierce, Christopher Perry, Ruining Wang, Jeffrey Zink, Carlotta A Glackin and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Nanoparticles Bounded to Interfering RNAs as a Therapy for Pancreatic Cancer: A Systematic Review.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Pooled it
  2. Article
  3. Article
  4. Review
  5. A Transcriptomic Analysis of Laryngeal Dysplasia.International journal of molecular sciences · 2024
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Cancers · 2021
    Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Hanmin WangDivision of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA 92354, USA.ORCID 0000-0002-4507-4201
Evgeny ChirshevDivision of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA 92354, USA.ORCID 0000-0002-3301-2724
Nozomi HojoDivision of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA 92354, USA.
Tise SuzukiDivision of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA 92354, USA.
Antonella BertucciDivision of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA 92354, USA.
Michael PierceDepartment of Biology, California State University San Bernardino, San Bernardino, CA 92407, USA.
Christopher PerryDivision of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA 92354, USA.
Ruining WangDepartment of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA.
Jeffrey ZinkDepartment of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA.
Carlotta A GlackinBeckman Research Institute, City of Hope, Duarte, CA 91016, USA.
Yevgeniya J IoffeDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Loma Linda University Medical Center, Loma Linda, CA 92354, USA.
Juli J UnternaehrerDivision of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA 92354, USA.ORCID 0000-0001-5864-4704
Loma Linda University · USUniversity of California, Los Angeles · USCalifornia State University, San Bernardino · USCity of Hope · USLoma Linda University Medical Center · US

Funding

California Institute for Regenerative Medicine DISC1-10588Loma Linda University 2140226, 2170240
6 · The paper itself

Abstract

We aimed to determine the mechanism of epithelial-mesenchymal transition (EMT)-induced stemness in cancer cells. Cancer relapse and metastasis are caused by rare stem-like cells within tumors. Studies of stem cell reprogramming have linked

Indexed as

epithelial–mesenchymal transitionmiRNAorthotopic patient-derived xenograftsovarian cancerstem cellstranscriptional regulation

Identifiers

PMID33806868
PMCPMC8004805
OpenAlexW3138192563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.