Evidence map›Paper›PMID 33806825›Full record

ReviewInternational journal of molecular sciences2021

The Pharmacology and Therapeutic Utility of Sodium Hydroselenide.

Kavitej Samra, Mathun Kuganesan, William Smith, Anna Kleyman, Robert Tidswell, Nishkantha Arulkumaran, Mervyn Singer, Alex Dyson

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. The Role of Selenium in Pathologies: An Updated Review.Antioxidants (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kavitej SamraBloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Gower Street, London WC1E 6BT, UK.
Mathun KuganesanBloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Gower Street, London WC1E 6BT, UK.
William SmithBloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Gower Street, London WC1E 6BT, UK.
Anna KleymanBloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Gower Street, London WC1E 6BT, UK.
Robert TidswellBloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Gower Street, London WC1E 6BT, UK.
Nishkantha ArulkumaranBloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Gower Street, London WC1E 6BT, UK.
Mervyn SingerBloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Gower Street, London WC1E 6BT, UK.
Alex DysonBloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Gower Street, London WC1E 6BT, UK.ORCID 0000-0001-8334-9432
Bury College · GB

Funding

Medical Research Council MR/S006737/1
6 · The paper itself

Abstract

Metabolically active gasotransmitters (nitric oxide, carbon monoxide and hydrogen sulfide) are important signalling molecules that show therapeutic utility in oxidative pathologies. The reduced form of selenium, hydrogen selenide (HSe

Indexed as

AnimalsAntioxidantsChemistry Techniques, SyntheticDose-Response Relationship, DrugDrug Evaluation, PreclinicalGene Expression RegulationHumansOxidation-ReductionOxidative StressSelenium CompoundsSelenoproteinsSodiumSodium SeleniteAntioxidantshydrogen selenideSelenium CompoundsSelenoproteinsSodiumSodium Selenitegasotransmittermitochondriareactive oxygen speciesseleniumselenoproteinssulfide

Identifiers

PMID33806825
PMCPMC8005069
OpenAlexW3139536413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.