Evidence map›Paper›PMID 33806820›Full record

ArticlePlants (Basel, Switzerland)2021

Differences in the Inhibitory Specificity Distinguish the Efficacy of Plant Protease Inhibitors on Mouse Fibrosarcoma.

Sonia Yoo Im, Camila Ramalho Bonturi, Adriana Miti Nakahata, Clóvis Ryuichi Nakaie, Arnildo Pott, Vali Joana Pott, Maria Luiza Vilela Oliva

Open access · goldAbstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sonia Yoo ImDepartamento de Bioquímica, Universidade Federal de São Paulo (UNIFESP), 04044-020 São Paulo, SP, Brazil.
Camila Ramalho BonturiDepartamento de Bioquímica, Universidade Federal de São Paulo (UNIFESP), 04044-020 São Paulo, SP, Brazil.
Adriana Miti NakahataLaboratório de Genômica e Biologia Molecular, Centro Internacional de Pesquisa (CIPE) do A.C.Camargo Cancer Center, 01508-010 São Paulo, SP, Brazil.
Clóvis Ryuichi NakaieDepartamento de Biofísica, Universidade Federal de São Paulo (UNIFESP), 04044-020 São Paulo, SP, Brazil.
Arnildo PottDepartamento de Biologia, Universidade Federal de Mato Grosso do Sul (UFMS), Cidade Universitária, 79070-900 Campo Grande, MS, Brazil.
Vali Joana PottDepartamento de Biologia, Universidade Federal de Mato Grosso do Sul (UFMS), Cidade Universitária, 79070-900 Campo Grande, MS, Brazil.
Maria Luiza Vilela OlivaDepartamento de Bioquímica, Universidade Federal de São Paulo (UNIFESP), 04044-020 São Paulo, SP, Brazil.ORCID 0000-0001-7346-6328
Universidade Federal de São Paulo · BRUniversidade Federal de Mato Grosso do Sul · BRAC Camargo Hospital · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 401452/2016-6Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance Code 001Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/07972-9, 2017/06630-7 and 2019/22243-9
6 · The paper itself

Abstract

Metastasis, the primary cause of death from malignant tumors, is facilitated by multiple protease-mediated processes. Thus, effort has been invested in the development of protease inhibitors to prevent metastasis. Here, we investigated the effects of protease inhibitors including the recombinant inhibitors rBbKI (serine protease inhibitor) and rBbCI (serine and cysteine inhibitor) derived from native inhibitors identified in

Indexed as

fibrosarcomametastasisnatural productsplantsprotease inhibitorstumor cells

Identifiers

PMID33806820
PMCPMC8005126
OpenAlexW3135975846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.