Evidence map›Paper›PMID 33806804›Full record

ArticleJournal of personalized medicine2021

Tumor Infiltrating Neutrophils Are Frequently Found in Adenocarcinomas of the Biliary Tract and Their Precursor Lesions with Possible Impact on Prognosis.

Vittorio Branchi, Benedict Jürgensen, Laura Esser, Maria Gonzalez-Carmona, Tobias J Weismüller, Christian P Strassburg, Jonas Henn, Alexander Semaan, Philipp Lingohr, Steffen Manekeller and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Personalized Medicine in Oncology; a Special Issue of theJournal of personalized medicine · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Vittorio BranchiDepartment of General, Visceral, Thoracic and Vascular Surgery, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0002-6182-835X
Benedict JürgensenDepartment of General, Visceral, Thoracic and Vascular Surgery, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0003-3642-3534
Laura EsserInstitute of Pathology, University Hospital Bonn, 53127 Bonn, Germany.
Maria Gonzalez-CarmonaDepartment of Internal Medicine I, University Hospital Bonn, 53127 Bonn, Germany.
Tobias J WeismüllerDepartment of Internal Medicine I, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0001-9736-1483
Christian P StrassburgDepartment of Internal Medicine I, University Hospital Bonn, 53127 Bonn, Germany.
Jonas HennDepartment of General, Visceral, Thoracic and Vascular Surgery, University Hospital Bonn, 53127 Bonn, Germany.
Alexander SemaanDepartment of General, Visceral, Thoracic and Vascular Surgery, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0001-5424-3217
Philipp LingohrDepartment of General, Visceral, Thoracic and Vascular Surgery, University Hospital Bonn, 53127 Bonn, Germany.
Steffen ManekellerDepartment of General, Visceral, Thoracic and Vascular Surgery, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0002-6159-4506
Glen KristiansenInstitute of Pathology, University Hospital Bonn, 53127 Bonn, Germany.
Jörg C KalffDepartment of General, Visceral, Thoracic and Vascular Surgery, University Hospital Bonn, 53127 Bonn, Germany.
Marieta I TomaInstitute of Pathology, University Hospital Bonn, 53127 Bonn, Germany.
Hanno MatthaeiDepartment of General, Visceral, Thoracic and Vascular Surgery, University Hospital Bonn, 53127 Bonn, Germany.
University Hospital Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biliary tract cancer (BTC) is characterized by an intense stromal reaction and a complex landscape of infiltrating immune cells. Evidence is emerging that tumor-infiltrating neutrophils (TINs) have an impact on carcinogenesis and tumor progression. TINs have also been associated with outcomes in various solid malignant tumors but their possible clinical role in BTC is largely unknown. Tissue samples from patients with sporadic BTC ("spBTC" cohort,

Indexed as

biliary tract cancercholangiocarcinomaneutrophilsprognosis

Identifiers

PMID33806804
PMCPMC8004909
OpenAlexW3137145109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.