Evidence map›Paper›PMID 33806762›Full record

SynthesisNutrients2021

Efficacy of Edible Bird's Nest on Cognitive Functions in Experimental Animal Models: A Systematic Review.

Maznah Ismail, Abdulsamad Alsalahi, Musheer Abdulwahid Aljaberi, Ramlah Mohamad Ibrahim, Faizah Abu Bakar, Aini Ideris

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Maznah IsmailLaboratory of Natural Medicines and Products, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400 UPM, Selangor, Malaysia.ORCID 0000-0002-2378-0519
Abdulsamad AlsalahiDepartment of Pharmacology, Faculty of Pharmacy, Sana'a University, Mazbah District, Sana'a 1247, Yemen.ORCID 0000-0002-2967-0556
Musheer Abdulwahid AljaberiDepartment of Community Health, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, Serdang 43400 UPM, Selangor, Malaysia.
Ramlah Mohamad IbrahimLaboratory of Natural Medicines and Products, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400 UPM, Selangor, Malaysia.
Faizah Abu BakarUZMA Clinic, Kelana Mall, SS6/12 Road, SS 6, Petaling Jaya 47301, Selangor, Malaysia.
Aini IderisDepartment of Veterinary Clinical Studies, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Serdang 43400 UPM, Selangor, Malaysia.
Universiti Putra Malaysia · MYSana'a University · YE

Funding

NKEA research grant scheme, Ministry of Agriculture and Agro-Based Industries Malay-sia and Swiftlet Centre of Excellence, UPM 6371400-10301-(2)
6 · The paper itself

Abstract

Edible bird's nest (EBN) is constructed from saliva of swiftlets birds and consumed largely by Southeast and East Asians for its nutritional value and anti-aging properties. Although the neuroprotection of EBN in animals has been reported, there has not been yet systemically summarized. Thus, this review systemically outlined the evidence of the neuroprotective activity of EBN in modulating the cognitive functions of either healthy or with induced-cognitive dysfunction animals as compared to placebos. The related records from 2010 to 2020 were retrieved from PubMed, Scopus, Web of Science and ScienceDirect using pre-specified keywords. The relevant records to the effect of EBN on cognition were selected according to the eligibility criteria and these studies underwent appraisal for the risk of bias. EBN improved the cognitive functions of induced-cognitive dysfunction and enhanced the cognitive performance of healthy animals as well as attenuated the neuroinflammations and neuro-oxidative stress in the hippocampus of these animals. Malaysian EBN could improve the cognitive functions of experimental animals as a treatment in induced cognitive dysfunction, a nutritional cognitive-enhancing agent in offspring and a prophylactic conservative effect on cognition against exposure to subsequent noxious cerebral accidents in a dose-depended manner through attenuating neuroinflammation and neuro-oxidative stress. This systemic review did not proceed meta-analysis.

Indexed as

BirdsCognitionFoodAnimalsDatabases, FactualHumansNutritive ValueOxidative StressSalivacognitionedible birds’ nestneurodegenerationneuroprotectionsystematic review

Identifiers

PMID33806762
PMCPMC8004720
OpenAlexW3139120249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.