Evidence map›Paper›PMID 33806736›Full record

ReviewMolecules (Basel, Switzerland)2021

Basic Principles in the Design of Spider Silk Fibers.

José Pérez-Rigueiro, Manuel Elices, Gustavo R Plaza, Gustavo V Guinea

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Relating spidroin motif prevalence and periodicity to the mechanical properties of major ampullate spider silks.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2023
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

José Pérez-RigueiroCentro de Tecnología Biomédica, Universidad Politécnica de Madrid, 28223 Madrid, Spain.
Manuel ElicesCentro de Tecnología Biomédica, Universidad Politécnica de Madrid, 28223 Madrid, Spain.
Gustavo R PlazaCentro de Tecnología Biomédica, Universidad Politécnica de Madrid, 28223 Madrid, Spain.ORCID 0000-0002-5555-5498
Gustavo V GuineaCentro de Tecnología Biomédica, Universidad Politécnica de Madrid, 28223 Madrid, Spain.ORCID 0000-0002-4326-3746
Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine · ESUniversidad Politécnica de Madrid · ES

Funding

Comunidad de Madrid NEUROCENTRO-B2017/BMD-3760Comunidad de Madrid Tec4Bio-CM/P2018/NMT-4443
6 · The paper itself

Abstract

The prominence of spider silk as a hallmark in biomimetics relies not only on its unrivalled mechanical properties, but also on how these properties are the result of a set of original design principles. In this sense, the study of spider silk summarizes most of the main topics relevant to the field and, consequently, offers a nice example on how these topics could be considered in other biomimetic systems. This review is intended to present a selection of some of the essential design principles that underlie the singular microstructure of major ampullate gland silk, as well as to show how the interplay between them leads to the outstanding tensile behavior of spider silk. Following this rationale, the mechanical behavior of the material is analyzed in detail and connected with its main microstructural features, specifically with those derived from the semicrystalline organization of the fibers. Establishing the relationship between mechanical properties and microstructure in spider silk not only offers a vivid image of the paths explored by nature in the search for high performance materials, but is also a valuable guide for the development of new artificial fibers inspired in their natural counterparts.

Indexed as

SpidersStress, MechanicalTensile StrengthAnimalsBiomimetic MaterialsSilkSilkmechanical propertiesspider silkspider silk standardization initiative (S3I)X ray diffraction

Identifiers

PMID33806736
PMCPMC8004941
OpenAlexW3136064135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.