ArticleBiosensors2021
A Cationic Surfactant-Decorated Liquid Crystal-Based Aptasensor for Label-Free Detection of Malathion Pesticides in Environmental Samples.
Article in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 43 citations in OpenAlex.
- Soft-interfaced liquid crystal microfluidics can probe the rigidity of lipid vesicles.Communications materials · 2026Article
- Harnessing the power of biosensors for environmental monitoring of pesticides in water.Applied microbiology and biotechnology · 2025Review
- ZnO-Polyaniline Nanocomposite Functionalised with Laccase Enzymes for Electrochemical Detection of Cetyltrimethylammonuium Bromide (CTAB).Journal of xenobiotics · 2024Article
- Highly sensitive and label-free detection of biotin using a liquid crystal-based optofluidic biosensor.Biomedical optics express · 2023Article
- Liquid crystal-based sensor for real-time detection of paraoxon pesticides based on acetylcholinesterase enzyme inhibition.Mikrochimica acta · 2023Article
- A comprehensive review on electrochemical and optical aptasensors for organophosphorus pesticides.Mikrochimica acta · 2022Review
- Label-free optical biosensors in the pandemic era.Nanophotonics (Berlin, Germany) · 2022Review
- Liquid Crystal Biosensors: Principles, Structure and Applications.Biosensors · 2022Review
- State-of-the-Art Development in Liquid Crystal Biochemical Sensors.Biosensors · 2022Review
- Determination of chlorothalonil levels through inhibitory effect on papain activity at protein-decorated liquid crystal interfaces.Mikrochimica acta · 2022Article
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2 authors at 1 institution in 1 country.
Funding
Abstract
We report a liquid crystal (LC)-based aptasensor for the detection of malathion using a cationic surfactant-decorated LC interface. In this method, LCs displayed dark optical images when in contact with aqueous cetyltrimethylammonium bromide (CTAB) solution due to the formation of a self-assembled CTAB monolayer at the aqueous/LC interface, which induced the homeotropic orientation of LCs. With the addition of malathion aptamer, the homeotropic orientation of LCs changed to a planar one due to the interactions between CTAB and the aptamer, resulting in a bright optical image. In the presence of malathion, the formation of aptamer-malathion complexes caused a conformational change of the aptamers, thereby weakening the interactions between CTAB and the aptamers. Therefore, CTAB is free to induce a homeotropic ordering of the LCs, which corresponds to a dark optical image. The developed sensor exhibited high specificity for malathion determination and a low detection limit of 0.465 nM was achieved. Moreover, the proposed biosensor was successfully applied to detect malathion in tap water, river water, and apple samples. The proposed LC-based aptasensor is a simple, rapid, and convenient platform for label-free monitoring of malathion in environmental samples.
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