ArticleJournal of clinical medicine2021
Cardiac Rupture-The Most Serious Complication of Takotsubo Syndrome: A Series of Five Cases and a Systematic Review.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Successful Treatment of Cardiogenic Shock Due to Cardiac Rupture by Transient Focal Mid-Ventricular Takotsubo Cardiomyopathy.JACC. Case reports · 2026Article
- Cardiac rupture due to Takotsubo syndrome complicated by a myocardial bridge: a case series.European heart journal. Case reports · 2026Article
- Ventricular Septal Perforation Associated with Takotsubo Syndrome and Its Pathogenic Mechanisms.Surgical case reports · 2026Article
- A rare case of left ventricular cardiac rupture in the acute phase of takotsubo syndrome.Journal of cardiology cases · 2026Article
- Takotsubo Cardiomyopathy Triggered by Electrical Cardioversion and Complicated by Ventricular Septal Rupture.CASE (Philadelphia, Pa.) · 2025Article
- Rescue of Acute VSD in Takotsubo Cardiomyopathy: The Role of BiPella Support in High-Risk Recovery.JACC. Case reports · 2025Article
- Incidence and risk factors for cardiac rupture after ST-segment elevation myocardial infarction in contemporary era: findings from the improving care for cardiovascular disease in China-Acute Coronary Syndrome project.Internal and emergency medicine · 2025Observational
- Article
- Delayed ventricular septal rupture complicated with ventricular aneurysm in a case of myocardial infarction with non-obstructive coronary arteries.BMC cardiovascular disorders · 2024Article
- Biventricular Takotsubo syndrome complicated with cardiogenic shock and ventricular septal rupture: a case report.European heart journal. Case reports · 2024Article
- Successful sutureless repair of multiple left ventricular free wall ruptures due to Takotsubo cardiomyopathy: a case report.Surgical case reports · 2024Article
- An Extensive Review on Imaging Diagnosis Methods in Takotsubo Syndrome.Reviews in cardiovascular medicine · 2023Review
- Takotsubo Syndrome: From Bench to Bedside and Bedside to Bench.Journal of clinical medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe most serious complication of the acute Takotsubo phase is a myocardial perforation, which is rare, but it usually results in the death of the patient.
methodsIn the years 2008-2020, 265 patients were added to the Podlasie Takotsubo Registry. Cardiac rupture was observed in five patients (1.89%), referred to as the Takotsubo syndrome with complications of cardiac rupture (TS+CR) group. The control group consisted of 50 consecutive patients with uncomplicated TS. The diagnosis of TS was based on the Mayo Clinic Criteria.
resultsCardiac rupture was observed in women with TS aged 74-88 years. Patients with TS and CR were older (82.20 vs. 64.84;
conclusionsCardiac rupture in TS is rare but is the most severe mechanical complication and is associated with a very high risk of death. The main risk factors for left ventricular perforation are female gender, older age, a higher concentration of cardiac enzymes, higher GRACE scores, and ST elevations shown using electrocardiogram (ECG).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.