Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
13 authors.
Celso AlvesMARE-Marine and Environmental Sciences Centre, Politécnico de Leiria, 2520-630 Peniche, Portugal.ORCID 0000-0003-1581-2127
Joana SilvaMARE-Marine and Environmental Sciences Centre, Politécnico de Leiria, 2520-630 Peniche, Portugal.ORCID 0000-0003-1224-1699
Susete PinteusMARE-Marine and Environmental Sciences Centre, Politécnico de Leiria, 2520-630 Peniche, Portugal.ORCID 0000-0002-3290-3111
Eva AlonsoDepartament of Pharmacology, Faculty of Veterinary, University of Santiago de Compostela, 27002 Lugo, Spain.ORCID 0000-0002-1131-6575
Rebeca AlvariñoDepartament of Pharmacology, Faculty of Veterinary, University of Santiago de Compostela, 27002 Lugo, Spain.ORCID 0000-0001-8796-1389
Adriana DuarteMARE-Marine and Environmental Sciences Centre, Politécnico de Leiria, 2520-630 Peniche, Portugal.
Diorge MarmittCell Culture Laboratory, Postgraduate Programme in Biotechnology, University of Vale do Taquari-Univates, Lajeado RS 95914-014, Brazil.
Márcia Inês GoettertCell Culture Laboratory, Postgraduate Programme in Biotechnology, University of Vale do Taquari-Univates, Lajeado RS 95914-014, Brazil.ORCID 0000-0002-3648-5033
Helena GasparMARE-Marine and Environmental Sciences Centre, Politécnico de Leiria, 2520-630 Peniche, Portugal.ORCID 0000-0002-1613-7023
Amparo AlfonsoDepartament of Pharmacology, Faculty of Veterinary, University of Santiago de Compostela, 27002 Lugo, Spain.ORCID 0000-0003-1572-9016
Maria C AlpoimCenter for Neuroscience and Cell Biology (CNC), University of Coimbra, 3004-517 Coimbra, Portugal.
Luis M BotanaDepartament of Pharmacology, Faculty of Veterinary, University of Santiago de Compostela, 27002 Lugo, Spain.ORCID 0000-0003-2153-6608
Rui PedrosaMARE-Marine and Environmental Sciences Centre, ESTM, Politécnico de Leiria, 2520-614 Peniche, Portugal.
Funding
Fundação para a Ciência e a Tecnologia PTDC/BIA-OUT/29250/2017Fundação para a Ciência e a Tecnologia SAICTPAC/0019/ 2015-LISBOA- 01-0145-FEDER-016405Fundação para a Ciência e a Tecnologia SFRH/BD/103255/2014Fundação para a Ciência e a Tecnologia UIDB/04046/2020Fundação para a Ciência e a Tecnologia UID/MAR/04292/2020Fundação para a Ciência e a Tecnologia UID/Multi/04046/2020
6 · The paper itself
Abstract
Marine natural products have exhibited uncommon chemical structures with relevant antitumor properties highlighting their potential to inspire the development of new anticancer agents. The goal of this work was to study the antitumor activities of the brominated diterpene sphaerodactylomelol, a rare example of the dactylomelane family. Cytotoxicity (10-100 µM; 24 h) was evaluated on tumor cells (A549, CACO-2, HCT-15, MCF-7, NCI-H226, PC-3, SH-SY5Y, SK-ML-28) and the effects estimated by MTT assay. Hydrogen peroxide (H
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Cytotoxic Mechanism of Sphaerodactylomelol, an Uncommon Bromoditerpene Isolated from · full record | OpenQuestion