Evidence map›Paper›PMID 33806376›Full record

ArticleJournal of fungi (Basel, Switzerland)2021

Atopic Dermatitis and Sensitisation to Molecular Components of

Jarmila Celakovska, Radka Vankova, Josef Bukac, Eva Cermakova, Ctirad Andrys, Jan Krejsek

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Characterisation ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The Role of the Cutaneous Mycobiome in Atopic Dermatitis.Journal of fungi (Basel, Switzerland) · 2022
    Review
  10. Article
  11. Article
  12. Journal of fungi (Basel, Switzerland) · 2022
    Review
  13. Article
  14. Special Issue: Host Defense against Fungi.Journal of fungi (Basel, Switzerland) · 2021
    Article
  15. Journal of fungi (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jarmila CelakovskaDepartment of Dermatology and Venereology, Faculty Hospital, Medical Faculty of Charles University, 50002 Hradec Králové, Czech Republic.
Radka VankovaDepartment of Clinical Immunology and Allergy, Faculty Hospital, Medical Faculty of Charles University, 50002 Hradec Králové, Czech Republic.
Josef BukacDepartment of Medical Biophysic, Medical Faculty of Charles University, 50002 Hradec Králové, Czech Republic.
Eva CermakovaDepartment of Medical Biophysic, Medical Faculty of Charles University, 50002 Hradec Králové, Czech Republic.
Ctirad AndrysDepartment of Clinical Immunology and Allergy, Faculty Hospital, Medical Faculty of Charles University, 50002 Hradec Králové, Czech Republic.
Jan KrejsekDepartment of Clinical Immunology and Allergy, Faculty Hospital, Medical Faculty of Charles University, 50002 Hradec Králové, Czech Republic.
Charles University · CZ

Funding

Progres, Charles University, Medical Faculty Hradec Kralove Q40/10
6 · The paper itself

Abstract

Progress in laboratory diagnostics of IgE-mediated allergies is being made through the use of component-resolved diagnosis. The aim of our study is to analyze the sensitization profile to allergen reagents in patients suffering from atopic dermatitis with the use of the ALEX 2-Allergy Explorer and especially to show the sensitization to molecular components of molds and yeast. The complete dermatological and allergological examination including the examination of the sensitization to allergen reagents with Allergy Explorer ALEX 2 testing was performed. The relation between the sensitization to molecular components of molds and yeast and the severity of atopic dermatitis, and the occurrence of bronchial asthma and allergic rhinitis was evaluated. Altogether, 100 atopic dermatitis patients were examined-48 men and 52 women, with an average age of 40.9 years. The sensitization to Mala s 6, Mala s 11, Sac c, Asp f 6, Cla h and Cla h 8 correlates to the severity of atopic dermatitis. The sensitization to Sac c, Alt a 6, Cla h, Cla h 8 was observed significantly more frequently in patients suffering from bronchial asthma to Mala s 6 in patients suffering from allergic rhinitis. In patients with severe form of atopic dermatitis (AD), a very high level of specific IgE was recorded to Mala s 11 (in 36%) and to Asp f 6 (in 12%).

Indexed as

ALEX 2–Allergy Explorerallergic rhinitisAlternariaAspergillusatopic dermatitisbronchial asthmaCladosporiumMalasseziamolecular componentsPenicillium

Identifiers

PMID33806376
PMCPMC8001933
OpenAlexW3134073578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.