Evidence map›Paper›PMID 33806205›Full record

ArticleNutrients2021

Multiple Micronutrients, Including Zinc, Selenium and Iron, Are Positively Associated with Anemia in New Zealand Aged Care Residents.

Sue O MacDonell, Jody C Miller, Michelle J Harper, Malcolm R Reid, Jillian J Haszard, Rosalind S Gibson, Lisa A Houghton

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
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  4. Abnormal erythrocyte-related parameters in children with Pb, Cr, Cu and Zn exposure.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sue O MacDonellDepartment of General Practice and Primary Care, School of Population Health, University of Auckland, Auckland 1072, New Zealand.ORCID 0000-0003-2359-2689
Jody C MillerDepartment of Human Nutrition, University of Otago, Dunedin 9054, New Zealand.
Michelle J HarperDepartment of Human Nutrition, University of Otago, Dunedin 9054, New Zealand.
Malcolm R ReidTrace Element Centre, Department of Chemistry, University of Otago, Dunedin 9054, New Zealand.ORCID 0000-0002-4129-0214
Jillian J HaszardDepartment of Human Nutrition, University of Otago, Dunedin 9054, New Zealand.ORCID 0000-0001-6312-7795
Rosalind S GibsonDepartment of Human Nutrition, University of Otago, Dunedin 9054, New Zealand.
Lisa A HoughtonDepartment of Human Nutrition, University of Otago, Dunedin 9054, New Zealand.
University of Otago · NZUniversity of Auckland · NZ

Funding

Lotteries Health New Zealand n/aUniversity of Otago Research Grant na
6 · The paper itself

Abstract

Anemia is a significant comorbidity for older adults not fully attributable to iron deficiency. Low-grade inflammation and other micronutrient deficiencies also contribute. This cross-sectional study examined the relationships between nutrient and non-nutrient factors with hemoglobin and anemia in 285 residents (>65 years) of 16 New Zealand aged-care facilities. Blood samples were analyzed for hemoglobin, ferritin, sTfR, hepcidin, zinc, selenium, and interleukin-6 (IL-6), (with ferritin, sTfR, zinc and selenium adjusted for inflammation). Linear regression models examined the relationships between micronutrient biomarkers (iron, zinc, selenium, vitamin B-12 and D), age, sex, and health factors with hemoglobin. Thirty-two percent of participants exhibited anemia, although <2% had either depleted iron stores or iron deficiency. Plasma zinc and selenium deficiencies were present in 72% and 38% of participants, respectively. Plasma zinc and total body iron (TBI) were positively associated (

Indexed as

AgedAged, 80 and overAnemiaBiomarkersCross-Sectional StudiesFemaleGeriatric AssessmentHomes for the AgedHumansIronMaleMicronutrientsNew ZealandNutritional StatusSeleniumZincBiomarkersIronMicronutrientsSeleniumZincanemiaanti-secretory medicationsinflammationinterleukin-6nursing homeproton pump inhibitorssoluble transferrin receptortotal body iron

Identifiers

PMID33806205
PMCPMC8066767
OpenAlexW3151800177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.