ArticleJournal of clinical medicine2021
Epidemiology and Viral Etiology of Pediatric Immune Thrombocytopenia through Korean Public Health Data Analysis.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 24 citations in OpenAlex.
- Immature Platelet Fraction and Absolute Immature Platelet Count as Diagnostic Markers in Pediatric Immune Thrombocytopenia.International journal of laboratory hematology · 2026Article
- Risk factors analysis and validation of early treatment non-response in children with primary ITP: a multicenter retrospective cohort study.Frontiers in immunology · 2026Article
- Novel murine model of human astrovirus infection reveals cardiovascular tropismJournal of virology · 2025Article
- Heat exposure and pediatric immune thrombocytopenia in Japan from 2011 to 2022: a nationwide space-timestratified case-crossover study.Haematologica · 2025Article
- The Many Faces of Immune Thrombocytopenia: Mechanisms, Therapies, and Clinical Challenges in Oncological Patients.Journal of clinical medicine · 2024Review
- An Investigation of the Relationship between Henoch-Schönlein Purpura and Viral Infection in Korea Using the Health Insurance Database.Journal of clinical medicine · 2024Article
- Advances in management of pediatric chronic immune thrombocytopenia: a narrative review.Journal of Yeungnam medical science · 2023Article
- Seasonal Trends in the Prevalence and Incidence of Viral Encephalitis in Korea (2015-2019).Journal of clinical medicine · 2023Article
- Immune thrombocytopenia and COVID-19 vaccination: Outcomes and comparisons to prepandemic patients.Research and practice in thrombosis and haemostasis · 2023Article
- Changes in the Incidence of Immune Thrombocytopenia in the Coronavirus Disease 2019 Era: A Nationwide Observational Study in Korea.Risk management and healthcare policy · 2023Article
- Management of immune thrombocytopenia: 2022 update of Korean experts recommendations.Blood research · 2022Review
- Severe Thrombocytopenic Purpura Associated with COVID-19 in a Pediatric Patient.Infection and drug resistance · 2022Article
- Beyond the Gastrointestinal Tract: The Emerging and Diverse Tissue Tropisms of Astroviruses.Viruses · 2021Review
- Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immune thrombocytopenic purpura (ITP) is prevalent in children aged 2-5 years but may occur in all pediatric age groups. In 50-60% of pediatric patients, ITP is preceded by an upper respiratory tract infection 1-4 weeks before its onset. In this study, the relationship between the development of ITP and viral infections in children was assessed. We analyzed data of 6487 patients aged < 18 years with incident ITP from the Health Insurance Review and Assessment Open Access Big Data Platform (2015 to 2018) and the Korea Disease Control and Prevention Agency. The monthly positive detection rate (PDR) of seven respiratory and four acute diarrhea viruses was calculated. The virus PDR seasonal trend data was analyzed through ARIMA modeling. The ITP diagnostic data and prevalence of viral infection 1 and 2 months prior were analyzed using the Granger test. The overall male to female (M/F) ratio was 1.2, whereas it was 1.4 in the youngest age group (< 1 year). The overall ITP incidence rate was 18.1 per 100,000 person-years. Respiratory syncytial virus, rhinovirus, rotavirus, and astrovirus infections influenced ITP occurrence in children. However, rotavirus infection is positively associated with the etiology of ITP after 1-2 months.
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