Evidence map›Paper›PMID 33806084›Full record

ArticleMolecules (Basel, Switzerland)2021

Comparative Analysis of Chemical Constituents in Different Parts of Lotus by UPLC and QToF-MS.

Haotian Pei, Wenyu Su, Meng Gui, Mingjie Dou, Yingxin Zhang, Cuizhu Wang, Dan Lu

Open access · goldAbstract readComparative Study
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Review
  3. Bio-guided discovery of antibacterial metabolites fromJournal of enzyme inhibition and medicinal chemistry · 2025
    Article
  4. Article
  5. Article
  6. The Manufacturing Process of Lotus (Foods (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Exploring the therapeutic potential ofFrontiers in pharmacology · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Metabolomic Profiling and Antioxidant Activities ofMolecules (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Haotian PeiSchool of Pharmaceutical Sciences, Jilin University, Fujin Road 1266, Changchun 130021, China.
Wenyu SuSchool of Pharmaceutical Sciences, Jilin University, Fujin Road 1266, Changchun 130021, China.
Meng GuiSchool of Pharmaceutical Sciences, Jilin University, Fujin Road 1266, Changchun 130021, China.
Mingjie DouSchool of Pharmaceutical Sciences, Jilin University, Fujin Road 1266, Changchun 130021, China.
Yingxin ZhangSchool of Pharmaceutical Sciences, Jilin University, Fujin Road 1266, Changchun 130021, China.
Cuizhu WangSchool of Pharmaceutical Sciences, Jilin University, Fujin Road 1266, Changchun 130021, China.ORCID 0000-0002-0694-4059
Dan LuSchool of Pharmaceutical Sciences, Jilin University, Fujin Road 1266, Changchun 130021, China.
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Six parts of lotus (seeds, leaves, plumule, stamens, receptacles and rhizome nodes) are herbal medicines that are listed in the Chinese Pharmacopoeia. Their indications and functions have been confirmed by a long history of clinical practice. To fully understand the material basis of clinical applications, UPLC-QToF-MS combined with the UNIFI platform and multivariate statistical analysis was used in this study. As a result, a total of 171 compounds were detected and characterized from the six parts, and 23 robust biomarkers were discovered. The method can be used as a standard protocol for the direct identification and prediction of the six parts of lotus. Meanwhile, these discoveries are valuable for improving the quality control method of herbal medicines. Most importantly, this was the first time that alkaloids were detected in the stamen, and terpenoids were detected in the cored seed. The stamen is a noteworthy part because it contains the greatest diversity of flavonoids and terpenoids, but research on the stamen is rather limited.

Indexed as

Chromatography, High Pressure LiquidFlavonoidsLotusMass SpectrometryTerpenesFlavonoidsTerpenesanalysisdifferent partslotusmetabolomicsphytochemicalsUPLC-QToF-MS

Identifiers

PMID33806084
PMCPMC8036816
OpenAlexW3151298621

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.