Evidence map›Paper›PMID 33806028›Full record

ArticleInternational journal of molecular sciences2021

Proteome of Stored RBC Membrane and Vesicles from Heterozygous Beta Thalassemia Donors.

Vassilis L Tzounakas, Alkmini T Anastasiadi, Monika Dzieciatkowska, Dimitrios G Karadimas, Konstantinos Stamoulis, Issidora S Papassideri, Kirk C Hansen, Angelo D'Alessandro, Anastasios G Kriebardis, Marianna H Antonelou

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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  4. It's in your blood: The impact of age, sex, genetic factors and exposures on stored red blood cell metabolism.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2024
    Review
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  6. Review
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  10. Red Blood Cell Omics and Machine Learning in Transfusion Medicine: Singularity Is Near.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2023
    Review
  11. In Sickness and in Health: Erythrocyte Responses to Stress and Aging.International journal of molecular sciences · 2022
    Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Vassilis L TzounakasDepartment of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), 15784 Athens, Greece.
Alkmini T AnastasiadiDepartment of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), 15784 Athens, Greece.
Monika DzieciatkowskaDepartment of Biochemistry and Molecular Genetics, School of Medicine-Anschutz Medical Campus, University of Colorado, Aurora, CO 80045, USA.
Dimitrios G KaradimasDepartment of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), 15784 Athens, Greece.
Konstantinos StamoulisHellenic National Blood Transfusion Centre, Acharnes, 13677 Athens, Greece.
Issidora S PapassideriDepartment of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), 15784 Athens, Greece.
Kirk C HansenDepartment of Biochemistry and Molecular Genetics, School of Medicine-Anschutz Medical Campus, University of Colorado, Aurora, CO 80045, USA.
Angelo D'AlessandroDepartment of Biochemistry and Molecular Genetics, School of Medicine-Anschutz Medical Campus, University of Colorado, Aurora, CO 80045, USA.ORCID 0000-0002-2258-6490
Anastasios G KriebardisLaboratory of Reliability and Quality Control in Laboratory Hematology (HemQcR), Department of Biomedical Sciences, School of Health & Welfare Sciences, University of West Attica (UniWA), 12243 Egaleo, Greece.
Marianna H AntonelouDepartment of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), 15784 Athens, Greece.ORCID 0000-0003-3787-3596
National and Kapodistrian University of Athens · GRUniversity of Colorado Anschutz Medical Campus · USUniversity of West Attica · GR

Funding

Quadrupole-Orbitrap Mass SpectrometerS10OD021641 · OD · UNIVERSITY OF COLORADO DENVER · PI HANSEN, KIRK C · 2017 to 2017
$600k
Hellenic Foundation for Research and Innovation (HFRI) and the General Secretariat for Research and Technology (GSRT) 2032NIH HHS S10 OD021641
6 · The paper itself

Abstract

Genetic characteristics of blood donors may impact the storability of blood products. Despite higher basal stress, red blood cells (RBCs) from eligible donors that are heterozygous for beta-thalassemia traits (βThal

Indexed as

Proteomebeta-ThalassemiaBlood DonorsBlood PreservationEnzyme-Linked Immunosorbent AssayErythrocyte MembraneExtracellular VesiclesHemolysisHeterozygoteHumansLeast-Squares AnalysisMembrane MicrodomainsOxidation-ReductionOxidative StressProteomicsSpecimen HandlingProteomebeta thalassemia trait donorsdonor variation effectextracellular vesicles proteomenetwork analysisRBC membrane proteomeRBC shape modificationsRBC storage lesion

Identifiers

PMID33806028
PMCPMC8037027
OpenAlexW3139075290

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.