Evidence map›Paper›PMID 33805935›Full record

ArticleMarine drugs2021

Antiplasmodial Compounds from Deep-Water Marine Invertebrates.

Amy E Wright, Jennifer E Collins, Bracken Roberts, Jill C Roberts, Priscilla L Winder, John K Reed, Maria Cristina Diaz, Shirley A Pomponi, Debopam Chakrabarti

Abstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amy E WrightHarbor Branch Oceanographic Institute, Florida Atlantic University, 5600 US Highway 1 North, Fort Pierce, FL 34946, USA.ORCID 0000-0003-4872-9776
Jennifer E CollinsBurnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32826, USA.ORCID 0000-0002-1195-4630
Bracken RobertsBurnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32826, USA.
Jill C RobertsHarbor Branch Oceanographic Institute, Florida Atlantic University, 5600 US Highway 1 North, Fort Pierce, FL 34946, USA.
Priscilla L WinderHarbor Branch Oceanographic Institute, Florida Atlantic University, 5600 US Highway 1 North, Fort Pierce, FL 34946, USA.
John K ReedHarbor Branch Oceanographic Institute, Florida Atlantic University, 5600 US Highway 1 North, Fort Pierce, FL 34946, USA.
Maria Cristina DiazHarbor Branch Oceanographic Institute, Florida Atlantic University, 5600 US Highway 1 North, Fort Pierce, FL 34946, USA.
Shirley A PomponiHarbor Branch Oceanographic Institute, Florida Atlantic University, 5600 US Highway 1 North, Fort Pierce, FL 34946, USA.
Debopam ChakrabartiBurnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32826, USA.ORCID 0000-0002-4554-3119

Funding

Marine Natural Products as AntimalarialsR21AI078376 · NIAID · UNIVERSITY OF CENTRAL FLORIDA · PI CHAKRABARTI, DEBOPAM · 2009 to 2010
$411k
Harbor Branch Oceanographic Institute Foundation Research ExcellenceNIH HHS 1RC2AT005917NIH HHS R21AI078376
6 · The paper itself

Abstract

Novel drug leads for malaria therapy are urgently needed because of the widespread emergence of resistance to all available drugs. Screening of the Harbor Branch enriched fraction library against the

Indexed as

AnimalsAnthozoaAntimalarialsDiterpenesHep G2 CellsHumansLife Cycle StagesMalaria, FalciparumMolecular StructurePlasmodium falciparumPoriferaStructure-Activity RelationshipTime FactorsAntimalarialsDiterpenesantiplasmodialBebryce grandisbebrycin Amalariamarine natural productniteninP. falciparumSpongia lamella

Identifiers

PMID33805935
PMCPMC8064351

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.