Evidence map›Paper›PMID 33805848›Full record

ArticleInternational journal of molecular sciences2021

Lantibiotics Produced by Oral Inhabitants as a Trigger for Dysbiosis of Human Intestinal Microbiota.

Hideo Yonezawa, Mizuho Motegi, Atsushi Oishi, Fuhito Hojo, Seiya Higashi, Eriko Nozaki, Kentaro Oka, Motomichi Takahashi, Takako Osaki, Shigeru Kamiya

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Regulatory effects of oral microbe on intestinal microbiota and the illness.Frontiers in cellular and infection microbiology · 2023
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hideo YonezawaDepartment of Infectious Diseases, Kyorin University School of Medicine, Tokyo 181-8611, Japan.ORCID 0000-0002-7989-9711
Mizuho MotegiDivision of Oral Restitution, Department of Pediatric Dentistry, Graduate School, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Atsushi OishiDivision of Oral Restitution, Department of Pediatric Dentistry, Graduate School, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Fuhito HojoInstitute of Laboratory Animals, Graduate School of Medicine, Kyorin University School of Medicine, Tokyo 181-8611, Japan.ORCID 0000-0001-7976-5927
Seiya HigashiCentral Research Institute, Miyarisan Pharmaceutical Co. Ltd., Tokyo 114-0016, Japan.
Eriko NozakiCore Laboratory for Proteomics and Genomics, Kyorin University School of Medicine, Tokyo 181-8611, Japan.
Kentaro OkaCentral Research Institute, Miyarisan Pharmaceutical Co. Ltd., Tokyo 114-0016, Japan.
Motomichi TakahashiDepartment of Infectious Diseases, Kyorin University School of Medicine, Tokyo 181-8611, Japan.
Takako OsakiDepartment of Infectious Diseases, Kyorin University School of Medicine, Tokyo 181-8611, Japan.ORCID 0000-0002-6430-4666
Shigeru KamiyaDepartment of Infectious Diseases, Kyorin University School of Medicine, Tokyo 181-8611, Japan.
Kyorin University · JPTokyo Medical and Dental University · JP

Funding

Japan Society for the Promotion of Science KAKENHI Grant Number 18K09890
6 · The paper itself

Abstract

Lantibiotics are a type of bacteriocin produced by Gram-positive bacteria and have a wide spectrum of Gram-positive antimicrobial activity. In this study, we determined that Mutacin I/III and Smb (a dipeptide lantibiotic), which are mainly produced by the widespread cariogenic bacterium

Indexed as

AnimalsAnti-Infective AgentsBacillotaBacteriocinsDysbiosisFecesFemaleGastrointestinal MicrobiomeMiceMice, Inbred ICRMouthRNA, Ribosomal, 16SStreptococcus mutansTemperatureAnti-Infective AgentsBacteriocinsmutacin IRNA, Ribosomal, 16SSmb lantibioticdysbiosisintestinal microbiotalantibioticsMutacinoral bacteriaSmb

Identifiers

PMID33805848
PMCPMC8037337
OpenAlexW3138149727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.