Evidence map›Paper›PMID 33805752›Full record

ArticleInternational journal of molecular sciences2021

Graphene Coating Obtained in a Cold-Wall CVD Process on the Co-Cr Alloy (L-605) for Medical Applications.

Łukasz Wasyluk, Vitalii Boiko, Marta Markowska, Mariusz Hasiak, Maria Luisa Saladino, Dariusz Hreniak, Matteo Amati, Luca Gregoratti, Patrick Zeller, Dariusz Biały and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Genotoxicity of Graphene-Based Materials.Nanomaterials (Basel, Switzerland) · 2022
    Review
  5. Carbon-Based Nanomaterials.International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Łukasz WasylukDivision of Optical Spectroscopy, Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Okólna 2, PL-50-422 Wrocław, Poland.
Vitalii BoikoDivision of Optical Spectroscopy, Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Okólna 2, PL-50-422 Wrocław, Poland.ORCID 0000-0001-6652-7890
Marta MarkowskaDivision of Optical Spectroscopy, Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Okólna 2, PL-50-422 Wrocław, Poland.
Mariusz HasiakDepartment of Mechanics, Materials Science and Biomedical Engineering, Wrocław University of Science and Technology, Smoluchowskiego 25, PL-50-370 Wrocław, Poland.ORCID 0000-0003-1093-6833
Maria Luisa SaladinoDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF) and INSTM UdR-Palermo, University of Palermo, Viale delle Scienze, Bld. 17, IT-90128 Palermo, Italy.ORCID 0000-0002-7481-8556
Dariusz HreniakDivision of Optical Spectroscopy, Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Okólna 2, PL-50-422 Wrocław, Poland.ORCID 0000-0003-1384-2314
Matteo AmatiElettra-Sincrotrone Trieste S.C.p.A., SS14-km 163.5 in Area Science Park, IT-34149 Trieste, Italy.ORCID 0000-0002-3809-2145
Luca GregorattiElettra-Sincrotrone Trieste S.C.p.A., SS14-km 163.5 in Area Science Park, IT-34149 Trieste, Italy.
Patrick ZellerElettra-Sincrotrone Trieste S.C.p.A., SS14-km 163.5 in Area Science Park, IT-34149 Trieste, Italy.
Dariusz BiałyCarbonmed Spółka z ograniczoną odpowiedzialnością, ul. Okólna 2, PL-50-422 Wrocław, Poland.ORCID 0000-0002-5191-4334
Jacek ArkowskiCarbonmed Spółka z ograniczoną odpowiedzialnością, ul. Okólna 2, PL-50-422 Wrocław, Poland.
Magdalena WawrzyńskaCarbonmed Spółka z ograniczoną odpowiedzialnością, ul. Okólna 2, PL-50-422 Wrocław, Poland.

Funding

Operational Program Smart Growth POIR.01.01.01-00-0319/17Università degli Studi di Palermo CORI-2018-C-D15-180463
6 · The paper itself

Abstract

Graphene coating on the cobalt-chromium alloy was optimized and successfully carried out by a cold-wall chemical vapor deposition (CW-CVD) method. A uniform layer of graphene for a large area of the Co-Cr alloy (discs of 10 mm diameter) was confirmed by Raman mapping coated area and analyzing specific G and 2D bands; in particular, the intensity ratio and the number of layers were calculated. The effect of the CW-CVD process on the microstructure and the morphology of the Co-Cr surface was investigated by scanning X-ray photoelectron microscope (SPEM), atomic force microscopy (AFM), scanning electron microscopy (SEM), and energy dispersive X-ray spectroscopy (EDS). Nanoindentation and scratch tests were performed to determine mechanical properties of Co-Cr disks. The results of microbiological tests indicate that the studied Co-Cr alloys covered with a graphene layer did not show a pro-coagulant effect. The obtained results confirm the possibility of using the developed coating method in medical applications, in particular in the field of cardiovascular diseases.

Indexed as

AnimalsBlood Coagulation FactorsBlood PlateletsCell SurvivalChromium AlloysCoated Materials, BiocompatibleErythrocytesGraphiteHumansMaterials TestingMiceNIH 3T3 CellsPartial Thromboplastin TimePlatelet ActivationPrimary Cell CultureSurface PropertiesBlood Coagulation FactorsChromium AlloysCoated Materials, BiocompatibleGraphitebiocompatibilitycobalt-chromium alloycold-wall chemical vapor deposition methodgraphene coating

Identifiers

PMID33805752
PMCPMC8001714

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.