Graphene Oxide-Induced Protein Conformational Change in Nasopharyngeal Carcinoma Cells: A Joint Research on Cytotoxicity and Photon Therapy.

Selvaraj Rajesh Kumar, Ya-Hui Hsu, Truong Thi Tuong Vi, Jong-Hwei Su Pang, Yao-Chang Lee, Chia-Hsun Hsieh, Shingjiang Jessie Lue

Abstract read

PubMed Full text at PMC Publisher

In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Selvaraj Rajesh KumarDepartment of Chemical and Materials Engineering, Chang Gung University, Wenhua 1st Road, Guishan, Taoyuan 333, Taiwan.ORCID 0000-0003-0822-7843

Ya-Hui HsuGraduate Institute of Clinical Medical Sciences, Chang Gung University, Wenhua 1st Road, Guishan, Taoyuan 333, Taiwan.

Truong Thi Tuong ViDepartment of Chemical and Materials Engineering, Chang Gung University, Wenhua 1st Road, Guishan, Taoyuan 333, Taiwan.

Jong-Hwei Su PangGraduate Institute of Clinical Medical Sciences, Chang Gung University, Wenhua 1st Road, Guishan, Taoyuan 333, Taiwan.

Yao-Chang LeeNational Synchrotron Radiation Research Center, Hsin Ann Road, Hsinchu City 300, Taiwan.ORCID 0000-0003-1761-3746

Chia-Hsun HsiehDivision of Hematology-Oncology, Department of Internal Medicine, New Taipei Municipal TuCheng Hospital, Jincheng Road, New Taipei City 236, Taiwan.ORCID 0000-0002-5547-409X

Shingjiang Jessie LueDepartment of Chemical and Materials Engineering, Chang Gung University, Wenhua 1st Road, Guishan, Taoyuan 333, Taiwan.ORCID 0000-0003-1950-8093

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objectives of this work aim to investigate the interaction and cytotoxicity between nanometric graphene oxide (GO) and nasopharyngeal carcinoma cells (NPC-BM1), and possible application in photon therapy. GO nanosheets were obtained in the size range of 100-200 nm, with a negative surface charge. This nanometric GO exhibited a limited (<10%) cytotoxicity effect and no significant dimensional change on NPC-BM1 cells in the tested GO concentration range (0.1-10 µg·mL

Indexed as

cancer cellscell viabilitygraphene oxide nanosheetsphoton therapysynchrotron radiation

Identifiers

PMID33805683

DOI10.3390/ma14061396

PMCPMC8001416

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.