ArticleJournal of clinical medicine2021
Effects of an Innovative Head-Up Tilt Protocol on Blood Pressure and Arterial Stiffness Changes.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 10 citations in OpenAlex.
- Splenic contraction associated with sudden, transient hypotension and sympathoexcitation in humans.Experimental physiology · 2026Article
- Personalized Protocol for the Dynamic Assessment of Functional Biomarkers of Vascular Stiffness: A Novel Diagnostic Tool in P4 Medicine.Diagnostics (Basel, Switzerland) · 2026Article
- Gender Difference in Orthostatic Vascular Stiffness Increase in Young Subjects.Diagnostics (Basel, Switzerland) · 2025Article
- The Importance of Orthostatic Increase in Pulse Wave Velocity in the Diagnosis of Early Vascular Aging.Journal of clinical medicine · 2024Article
- Preclinical Orthostatic Abnormalities May Predict Early Increase in Vascular Stiffness in Different Age Groups: A Pilot Study.Diagnostics (Basel, Switzerland) · 2023Article
- Article
- Effects of trunk posture on cardiovascular and autonomic nervous systems: A pilot study.Frontiers in physiology · 2022Article
- Support Vector Machine-Based Classification of Vasovagal Syncope Using Head-Up Tilt Test.Biology · 2021Article
- Autoimmune Rheumatic Diseases and Vascular Function: The Concept of Autoimmune Atherosclerosis.Journal of clinical medicine · 2021Review
- Association of free fatty acid binding protein with central aortic stiffness, myocardial dysfunction and preserved ejection fraction heart failure.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of our study was to identify blood pressure (BP) and pulse wave velocity (PWV) changes during orthostatic loading, using a new the head-up tilt test (HUTT), which incorporates the usage of a standardized hydrostatic column height.
methods40 healthy subjects 20-32 years performed HUTT, which was standardized to a height of the hydrostatic column at 133 cm. Exposure time was 10 min in each of 3 positions: horizontal supine 1, HUTT, and horizontal supine 2. The individual tilt up angle made it possible to set the standard value of the hydrostatic column. Hemodynamic parameters were recorded beat to beat using "Task Force Monitor 3040 i", pulse-wave velocity (PWV) was measured with a sphygmograph-sphygmomanometer VaSera VS1500N.
resultsOrthostatic loading caused a significant increase in heart rate (HR) and a decrease in stroke volume (SV) (
conclusionThe new test protocol involving HUTT standardized to a height of hydrostatic column at 133 cm causes typical hemodynamics responses during orthostatic loading. Individual analysis of the subjects revealed subclinical orthostatic disorders (OSD) in up to 52% of the test persons. During HUTT, all test subjects showed a significant increase in PWV. The new innovative HUTT protocol can be applied in multi-center studies in healthy subjects to detect preclinical forms of orthostatic disorders under standard gravity load conditions.
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