Evidence map›Paper›PMID 33805417›Full record

ArticleViruses2021

Stable Display of Artificially Long Foreign Antigens on Chimeric

Tsung-Hsien Chen, Chung-Chi Hu, Chin-Wei Lee, Yu-Min Feng, Na-Sheng Lin, Yau-Heiu Hsu

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Tsung-Hsien ChenGraduate Institute of Biotechnology, National Chung Hsing University, Taichung 40227, Taiwan.ORCID 0000-0002-1542-1495
Chung-Chi HuGraduate Institute of Biotechnology, National Chung Hsing University, Taichung 40227, Taiwan.
Chin-Wei LeeGraduate Institute of Biotechnology, National Chung Hsing University, Taichung 40227, Taiwan.
Yu-Min FengDepartment of Internal Medicine, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi 60002, Taiwan.
Na-Sheng LinInstitute of Plant and Microbial Biology, Academia Sinica, Taipei 11529, Taiwan.
Yau-Heiu HsuGraduate Institute of Biotechnology, National Chung Hsing University, Taichung 40227, Taiwan.
National Chung Hsing University · TWChia-Yi Christian Hospital · TWInstitute of Plant and Microbial Biology, Academia Sinica · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant viruses can be genetically modified to generate chimeric virus particles (CVPs) carrying heterologous peptides fused on the surface of coat protein (CP) subunits as vaccine candidates. However, some factors may be especially significant in determining the properties of chimeras. In this study, peptides from various sources and of various lengths were inserted into the Bamboo mosaic virus

Indexed as

Antigens, ViralCapsid ProteinsEpitopesFoot-and-Mouth Disease VirusPlant VirusesPotexvirusVaccines, SyntheticVirionAntigens, ViralCapsid ProteinsEpitopesVaccines, SyntheticVP1 protein, Foot-and-mouth disease virusBamboo mosaic viruschimeric virus particles (CVPs)flexible linkerlonger antigenspeptide propertiesvirus accumulation

Identifiers

PMID33805417
PMCPMC8067224
OpenAlexW3140271706

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.