Evidence map›Paper›PMID 33805350›Full record

ArticleBrain sciences2021

Neural Oscillation Associated with Contagious Itch in Patients with Atopic Dermatitis.

In-Seon Lee, Kyuseok Kim, Hi-Joon Park, Hyangsook Lee, Won-Mo Jung, Do-Won Kim, Younbyoung Chae

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

In-Seon LeeAcupuncture and Meridian Science Research Center, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0001-9275-3111
Kyuseok KimDepartment of Ophthalmology, Otorhinolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Hi-Joon ParkAcupuncture and Meridian Science Research Center, Kyung Hee University, Seoul 02447, Korea.
Hyangsook LeeAcupuncture and Meridian Science Research Center, Kyung Hee University, Seoul 02447, Korea.
Won-Mo JungAcupuncture and Meridian Science Research Center, Kyung Hee University, Seoul 02447, Korea.
Do-Won KimDepartment of Biomedical Engineering, Chonnam National University, Yeosu 59626, Korea.
Younbyoung ChaeAcupuncture and Meridian Science Research Center, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0001-6787-2215
Kyung Hee University · KRChonnam National University · KR

Funding

National Research Foundation of Korea NRF-2015M3A9E052338, 2020R1A4A1018598
6 · The paper itself

Abstract

objectiveItch is an unpleasant sensation associated with an urge to scratch and is a major health care issue associated with atopic dermatitis (AD). Contagious itch, i.e., subjective feelings of itchiness induced by watching others' scratching behavior, is common in patients with AD. Using electroencephalography, we examined alpha (8-13 Hz) oscillations in sensorimotor areas associated with the desire to scratch in patients with AD.

methodsThirty-six patients with AD and 34 healthy controls (HCs) participated in this study. They evaluated their itch levels after watching short videos of a model scratching or tapping parts of his body. Neural oscillations were recorded from nine electrodes, including those placed over sensorimotor areas. Time-frequency analysis was used to compare mu rhythm suppression over the sensorimotor areas in response to these videos between patients with AD and HCs.

resultsThe behavioral test showed that the visual stimuli induced increased feelings of itchiness in patients with AD relative to HCs under the tapping and scratching conditions. The time-frequency analysis revealed that mu rhythm suppression in response to scratching images was significantly prominent in patients with AD, but not in HCs.

conclusionPatients with AD exhibited increased susceptibility to contagious itch. This phenomenon might be related to enhanced mu rhythm suppression in sensorimotor areas of the brain in these patients. Our findings provide new insight into the neurophysiological basis of itch sensations in patients with AD.

Indexed as

atopic dermatitiscontagious itchelectroencephalographymu rhythmtime–frequency analysis

Identifiers

PMID33805350
PMCPMC8067125
OpenAlexW3146881640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.