Evidence map›Paper›PMID 33805313›Full record

ArticleJournal of personalized medicine2021

ScanBious: Survey for Obesity Genes Using PubMed Abstracts and DisGeNET.

Svetlana Tarbeeva, Ekaterina Lyamtseva, Andrey Lisitsa, Anna Kozlova, Elena Ponomarenko, Ekaterina Ilgisonis

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Food for Thought: Proteomics for Meat Safety.Life (Basel, Switzerland) · 2023
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Svetlana TarbeevaInternational School "Medicine of the Future", Sechenov University, 119991 Moscow, Russia.
Ekaterina LyamtsevaInstitute of Biology, Tyumen State University, 625003 Tyumen, Russia.
Andrey LisitsaInstitute of Biomedical Chemistry, 119121 Moscow, Russia.
Anna KozlovaInstitute of Biomedical Chemistry, 119121 Moscow, Russia.
Elena PonomarenkoInstitute of Biomedical Chemistry, 119121 Moscow, Russia.
Ekaterina IlgisonisInstitute of Biomedical Chemistry, 119121 Moscow, Russia.

Funding

Russian Foundation for Basic Research 19-29-01138
6 · The paper itself

Abstract

We used automatic text-mining of PubMed abstracts of papers related to obesity, with the aim of revealing that the information used in abstracts reflects the current understanding and key concepts of this widely explored problem. We compared expert data from DisGeNET to the results of an automated MeSH (Medical Subject Heading) search, which was performed by the ScanBious web tool. The analysis provided an overview of the obesity field, highlighting major trends such as physiological conditions, age, and diet, as well as key well-studied genes, such as adiponectin and its receptor. By intersecting the DisGeNET knowledge with the ScanBious results, we deciphered four clusters of obesity-related genes. An initial set of 100+ thousand abstracts and 622 genes was reduced to 19 genes, distributed among just a few groups: heredity, inflammation, intercellular signaling, and cancer. Rapid profiling of articles could drive personalized medicine: if the disease signs of a particular person were superimposed on a general network, then it would be possible to understand which are non-specific (observed in cohorts and, therefore, most likely have known treatment solutions) and which are less investigated, and probably represent a personalized case.

Indexed as

data-mininggene networkMeSHobesitytext-mining

Identifiers

PMID33805313
PMCPMC8065449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.