Evidence map›Paper›PMID 33805296›Full record

ArticleInternational journal of molecular sciences2021

Comparison of Cerebellar Grey Matter Alterations in Bipolar and Cerebellar Patients: Evidence from Voxel-Based Analysis.

Michela Lupo, Giusy Olivito, Andrea Gragnani, Marco Saettoni, Libera Siciliano, Corinna Pancheri, Matteo Panfili, Marco Bozzali, Roberto Delle Chiaie, Maria Leggio

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
6.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Possible compensatory role of cerebellum in bipolar disorder. A cortical thickness study.European archives of psychiatry and clinical neuroscience · 2026
    Article
  3. Article
  4. A Virtual In Vivo Dissection and Analysis of Socioaffective Symptoms Related to Cerebellum-Midbrain Reward Circuitry in Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  5. Review
  6. AnbioRxiv : the preprint server for biology · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. A missing link in affect regulation: the cerebellum.Social cognitive and affective neuroscience · 2022
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Michela LupoAtaxia Laboratory, Fondazione Santa Lucia IRCCS, 00179 Rome, Italy.ORCID 0000-0003-2971-0914
Giusy OlivitoAtaxia Laboratory, Fondazione Santa Lucia IRCCS, 00179 Rome, Italy.
Andrea GragnaniScuola di Psicoterapia Cognitiva SPC, 58100 Grosseto, Italy.ORCID 0000-0001-9129-8794
Marco SaettoniScuola di Psicoterapia Cognitiva SPC, 58100 Grosseto, Italy.
Libera SicilianoPhD Program in Behavioral Neuroscience, Sapienza University of Rome, 00185 Rome, Italy.
Corinna PancheriDepartement of Neuroscience and Mental Health-Policlinico Umberto I Hospital, Sapienza University of Rome, 00161 Rome, Italy.
Matteo PanfiliDepartement of Neuroscience and Mental Health-Policlinico Umberto I Hospital, Sapienza University of Rome, 00161 Rome, Italy.
Marco BozzaliClinical Imaging Science Center, Brighton and Sussex Medical School, Brighton BN1 9RR, UK.
Roberto Delle ChiaieDepartement of Neuroscience and Mental Health-Policlinico Umberto I Hospital, Sapienza University of Rome, 00161 Rome, Italy.
Maria LeggioAtaxia Laboratory, Fondazione Santa Lucia IRCCS, 00179 Rome, Italy.ORCID 0000-0003-3750-2760
Fondazione Santa Lucia · ITPoliclinico Umberto I · ITCentro di Terapia Metacognitiva Interpersonale · ITBrighton and Sussex Medical School · GBSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to compare the patterns of cerebellar alterations associated with bipolar disease with those induced by the presence of cerebellar neurodegenerative pathologies to clarify the potential cerebellar contribution to bipolar affective disturbance. Twenty-nine patients affected by bipolar disorder, 32 subjects affected by cerebellar neurodegenerative pathologies, and 37 age-matched healthy subjects underwent a 3T MRI protocol. A voxel-based morphometry analysis was used to show similarities and differences in cerebellar grey matter (GM) loss between the groups. We found a pattern of GM cerebellar alterations in both bipolar and cerebellar groups that involved the anterior and posterior cerebellar regions (

Indexed as

AdultAtrophyBipolar DisorderCerebellar DiseasesCerebellumFemaleGray MatterHumansMagnetic Resonance ImagingMaleMiddle AgedNeurodegenerative Diseasesbipolar disordercerebellar atrophycerebellar grey matter volumevoxel-based morphometry

Identifiers

PMID33805296
PMCPMC8036397
OpenAlexW3146943857

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.