ReviewChildren (Basel, Switzerland)2021
Long-Term Outcomes and the Post-Intensive Care Syndrome in Critically Ill Children: A North American Perspective.
Review in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026.Intensive care medicine · 2026Pooled it
- Erector spinae plane block versus intravenous opioid for analgesia in pediatric cardiac surgery: A systematic review and meta-analysis.Paediatric anaesthesia · 2025Pooled it
- Correlation of parent-reported physical health-related quality-of-life with quantitatively measured physical function of former critically ill children.Journal of patient-reported outcomes · 2026Trial
- Developmental Care in the Early Years in Pediatric Intensive Care Patients as a Strategy to Mitigate Pediatric Post-Intensive-Care Syndrome: A Narrative Review.Journal of intensive care medicine · 2026Review
- Discordance between early mobility protocol expectations and nurse-led mobilizations of critically ill children: A quality improvement initiative.World journal of critical care medicine · 2026Article
- Current applications and future perspectives of family-integrated care in the pediatric intensive care unit: a narrative review from concept to practice.Translational pediatrics · 2026Review
- Post-intensive care sequelae after severe bacterial infections in previously healthy children.Molecular and cellular pediatrics · 2026Article
- Early Gut Microbiome-Short-Chain Fatty Acid Axis Disruption May Be Associated with Delayed Recovery in Critically Ill Children.Nutrients · 2026Observational
- Changes in Academic Standardized Testing After Pediatric Intensive Care.JAMA network open · 2026Article
- Article
- Clinical features of pediatric patients with prolonged Pediatric Intensive Care Unit stay.Revista medica del Instituto Mexicano del Seguro Social · 2026Article
- Nurses` perspectives on early mobilization of intubated children in the pediatric intensive care unit: a qualitative study of barriers and facilitators.Frontiers in pediatrics · 2026Article
- Post-Intensive Care Syndrome in Pediatric Neurovascular Patients: A Qualitative Study of Parent Experiences.Cureus · 2025Article
- Discharge Screening Predicts Persistent Parental Psychological Distress After Pediatric Critical Illness.Children (Basel, Switzerland) · 2025Article
- Beyond Staying Alive….Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025Article
- Parental presence in the pediatric intensive care unit reduces postoperative sedative requirements: A retrospective study.World journal of clinical pediatrics · 2025Article
- [Self-reported quality of life of pediatric patients discharged from the Intensive Care Unit].Revista espanola de salud publica · 2025Observational
- Effect of educational program on nurses' performance regarding application of liberation bundle in pediatric intensive care unit.BMC nursing · 2025Article
- Regional anesthesia for pediatric cardiac surgery: a review.BMC anesthesiology · 2025Review
- Nutritional Intake in Venovenous ECMO Patients: A Single-Center Study in a North American PICU.Nutrients · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advances in medical and surgical care for children in the pediatric intensive care unit (PICU) have led to vast reductions in mortality, but survivors often leave with newly acquired or worsened morbidity. Emerging evidence reveals that survivors of pediatric critical illness may experience a constellation of physical, emotional, cognitive, and social impairments, collectively known as the "post-intensive care syndrome in pediatrics" (PICs-P). The spectrum of PICs-P manifestations within each domain are heterogeneous. This is attributed to the wide age and developmental diversity of children admitted to PICUs and the high prevalence of chronic complex conditions. PICs-P recovery follows variable trajectories based on numerous patient, family, and environmental factors. Those who improve tend to do so within less than a year of discharge. A small proportion, however, may actually worsen over time. There are many gaps in our current understanding of PICs-P. A unified approach to screening, preventing, and treating PICs-P-related morbidity has been hindered by disparate research methodology. Initiatives are underway to harmonize clinical and research priorities, validate new and existing epidemiologic and patient-specific tools for the prediction or monitoring of outcomes, and define research priorities for investigators interested in long-term outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.