ReviewAntioxidants (Basel, Switzerland)2021
Impact of Polyphenolic-Food on Longevity: An Elixir of Life. An Overview.
Review in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 3 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Pooled it
- Pooled it
- Complementary and Alternative Therapies for Weight Loss: A Narrative Review.Journal of evidence-based integrative medicinePooled it
- Dietary Microplastic Exposure in Athletes: Implications for Metabolism, Gut Health, and Performance.Nutrients · 2026Review
- Wild blueberry-derived polyphenol metabolites attenuate telomere shortening in an in vitro model of metabolic syndrome.European journal of nutrition · 2026Article
- Unlocking the Secrets of Nature: Phytochemicals as Key Players in Longevity and Healthy Aging.Cell biochemistry and biophysics · 2026Review
- Ethyl Acetate Extract ofCurrent issues in molecular biology · 2025Article
- Unlocking Polyphenol Efficacy: The Role of Gut Microbiota in Modulating Bioavailability and Health Effects.Nutrients · 2025Review
- Advances in Longevity: The Intersection of Regenerative Medicine and Cosmetic Dermatology.Journal of cosmetic dermatology · 2025Review
- Mediterranean Diet and Agri-Food By-Products: A Possible Sustainable Approach for Breast Cancer Treatment.Antioxidants (Basel, Switzerland) · 2025Review
- Main Dietary Patterns for Healthy Aging and Well-Being.Nutrients · 2025Review
- Associations between flavonoid-rich food and flavonoid intakes and incident unhealthy aging outcomes in older United States males and females.The American journal of clinical nutrition · 2025Article
- The Role of Plant-Based Nutrition and Exercise in Metabolic Syndrome: A Narrative Review.Nutrients · 2025Review
- Dietary Phyllanthus Emblica inclusion regulates growth, serum biochemistry, organ histology, gene expression, and resistance against Aspergillus Flavus in Nile Tilapia (Oreochromis Niloticus).Scientific reports · 2025Article
- Resveratrol and Physical Activity: A Successful Combination for the Maintenance of Health and Wellbeing?Nutrients · 2025Review
- Crosstalk Between Antioxidants and Adipogenesis: Mechanistic Pathways and Their Roles in Metabolic Health.Antioxidants (Basel, Switzerland) · 2025Review
- Crosstalk between adipogenesis and aging: role of polyphenols in combating adipogenic-associated aging.Immunity & ageing : I & A · 2024Review
- The Impact of the Mediterranean Diet on Telomere Biology: Implications for Disease Management-A Narrative Review.Nutrients · 2024Review
- Dietary Phenolic Compounds-Wellbeing and Perspective Applications.International journal of molecular sciences · 2024Review
- Harmony in Motion: Unraveling the Nexus of Sports, Plant-Based Nutrition, and Antioxidants for Peak Performance.Antioxidants (Basel, Switzerland) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aging and, particularly, the onset of age-related diseases are associated with tissue dysfunction and macromolecular damage, some of which can be attributed to accumulation of oxidative damage. Recently, growing interest has emerged on the beneficial effects of plant-based diets for the prevention of chronic diseases including obesity, diabetes, and cardiovascular disease. Several studies collectively suggests that the intake of polyphenols and their major food sources may exert beneficial effects on improving insulin resistance and related diabetes risk factors, such as inflammation and oxidative stress. They are the most abundant antioxidants in the diet, and their intake has been associated with a reduced aging in humans. Polyphenolic intake has been shown to be effective at ameliorating several age-related phenotypes, including oxidative stress, inflammation, impaired proteostasis, and cellular senescence, both in vitro and in vivo. In this paper, effects of these phytochemicals (either pure forms or polyphenolic-food) are reviewed and summarized according to affected cellular signaling pathways. Finally, the effectiveness of the anti-aging preventive action of nutritional interventions based on diets rich in polyphenolic food, such as the diets of the Blue zones, are discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.