Evidence map›Paper›PMID 33805042›Full record

ArticleInternational journal of molecular sciences2021

Transient Receptor Potential Ankyrin 1 (TRPA1)-An Inflammation-Induced Factor in Human HaCaT Keratinocytes.

Samu Luostarinen, Mari Hämäläinen, Eeva Moilanen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. The regulation of TRPA1 expression and function by Th1 and Th2-type inflammation in human A549 lung epithelial cells.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Article
  10. Article
  11. Article
  12. Inflammation-the role of TRPA1 channel.Frontiers in physiology · 2023
    Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Samu LuostarinenThe Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 33014 Tampere, Finland.
Mari HämäläinenThe Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 33014 Tampere, Finland.
Eeva MoilanenThe Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 33014 Tampere, Finland.ORCID 0000-0002-8577-0316
Tampere University · FI

Funding

Academy of FinlandCompetitive State Research Financing of the Expert Responsibility Area of Tampere University HospitalResearch Foundation 300 of Rheumatic Diseases, FinlandTampere Tuberculosis Foundation
6 · The paper itself

Abstract

Transient receptor potential ankyrin 1 (TRPA1) is an ion channel mainly studied in sensory neurons where it mediates itch, pain and neurogenic inflammation. Recently, some nonneuronal cells have also been shown to express

Indexed as

AnimalsBiopsyCalcineurin InhibitorsChemokine CCL2FemaleGlucocorticoidsHaCaT CellsHEK293 CellsHumansInflammationKeratinocytesMAP Kinase Signaling SystemMiceMice, KnockoutNF-kappa BSkinCalcineurin InhibitorsCCL2 protein, humanCcl2 protein, mouseChemokine CCL2GlucocorticoidsNF-kappa BTRPA1 Cation ChannelTRPA1 protein, humanTrpa1 protein, mousecalcineurin inhibitorsglucocorticoidsinflammationtransient receptor potential ankyrin 1 (TRPA1) cation channeltumor necrosis factor (TNF)

Identifiers

PMID33805042
PMCPMC8037497
OpenAlexW3139184645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.