Evidence map›Paper›PMID 33805020›Full record

ReviewInternational journal of molecular sciences2021

Post-Transcriptional Regulation of

Angela K Odle, Melanie C MacNicol, Gwen V Childs, Angus M MacNicol

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Angela K OdleDepartment of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.ORCID 0000-0001-5017-9676
Melanie C MacNicolDepartment of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Gwen V ChildsDepartment of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Angus M MacNicolDepartment of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
University of Arkansas for Medical Sciences · US

Funding

Center for Translational NeuroscienceP20GM103425 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI GARCIA-RILL, EDGAR E. · 2012 to 2013
$4.1M
Control of pituitary cell plasticity through regulated mRNA translationR01HD093461 · NICHD · UNIV OF ARKANSAS FOR MED SCIS · PI CHILDS, GWEN V, MACNICOL, ANGUS M · 2018 to 2022
$3.1M
Post-transcriptional Pathways that Signal Leptin Regulation of GonadotropesR01HD087057 · NICHD · UNIV OF ARKANSAS FOR MED SCIS · PI CHILDS, GWEN V, MACNICOL, ANGUS M · 2016 to 2020
$2.3M
The Impact of Obesity on Somatotrope FunctionR01DK127723 · NIDDK · UNIV OF ARKANSAS FOR MED SCIS · PI CHILDS, GWEN V, MACNICOL, ANGUS M · 2021 to 2024
$2.3M
Tropic Roles for Leptin in the Maturation of SomatotropesR01DK113776 · NIDDK · UNIV OF ARKANSAS FOR MED SCIS · PI CHILDS, GWEN V, MACNICOL, ANGUS M · 2017 to 2020
$1.8M
The Significance of Leptin Signals to Neonatal Somatotropes and GonadotropesR01HD059056 · NICHD · UNIV OF ARKANSAS FOR MED SCIS · PI CHILDS, GWEN V · 2009 to 2013
$1.4M
KINETICS AND BLOCKADE IN A CA++-ACTIVATED K+ CHANNELF32GM011070 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KIRBER, MICHAEL T · 1985 to 1986
–
NICHD NIH HHS R01 HD059056NICHD NIH HHS R01 HD087057NICHD NIH HHS R01 HD093461NIDDK NIH HHS R01 DK113776NIDDK NIH HHS R01DK113776NIDDK NIH HHS R01 DK127723NIGMS NIH HHS P20GM103425NIGMS NIH HHS P30GM11070
6 · The paper itself

Abstract

The proper expression of gonadotropin-releasing hormone receptors (GnRHRs) by pituitary gonadotropes is critical for maintaining maximum reproductive capacity. GnRH receptor expression must be tightly regulated in order to maintain the normal pattern of expression through the estrous cycle in rodents, which is believed to be important for interpreting the finely tuned pulses of GnRH from the hypothalamus. Much work has shown that

Indexed as

Gene Expression RegulationReproduction3' Untranslated RegionsAdipokinesAnimalsEstrusFemaleGonadotropin-Releasing HormoneHumansHypothalamusLeptinMicePituitary GlandRatsReceptors, LHRHRNA, Messenger3' Untranslated RegionsAdipokinesGNRHR protein, humanGonadotropin-Releasing HormoneLeptinReceptors, LHRHRNA, Messengergonadotropin-releasing hormone receptorleptinpost-transcriptional control

Identifiers

PMID33805020
PMCPMC8038027
OpenAlexW3136120216

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.