ReviewBiomolecules2021
Biological Rhythm and Chronotype: New Perspectives in Health.
Review in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 159 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
159 citing papers in PubMed, 10 syntheses or guidelines pooled it, 332 citations in OpenAlex.
- Chronotype and disordered eating indicators: A systematic review and meta-analysis.Clinical psychology review · 2026Pooled it
- Food Intake According to Clock Gene Polymorphisms: A Systematic Review.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Pooled it
- Sleep and the Mediterranean diet: A systematic review and meta-analysis.Sleep medicine reviews · 2025Pooled it
- Chrono-optimizing vaccine administration: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Human melanopsin (OPN4) gene polymorphisms: a systematic review.Frontiers in neuroscience · 2025Pooled it
- Association Between Sleep Duration and Low Bone Mineral Density and Osteoporosis: A Systematic Review and Meta-analysis.Calcified tissue international · 2024Pooled it
- The research progress and prospects of circadian rhythm in obesity: a bibliometric analysis.Frontiers in nutrition · 2024Pooled it
- Physiological Rhythms and Biological Variation of Biomolecules: The Road to Personalized Laboratory Medicine.International journal of molecular sciences · 2023Pooled it
- Sleep and spa therapies: What is the role of balneotherapy associated with exercise? A systematic review.Frontiers in physiology · 2022Pooled it
- The association between metabolic parameters and evening chronotype and social jetlag in non-shift workers: A meta-analysis.Frontiers in endocrinology · 2022Pooled it
- Chronotype-aligned exercise timing in middle-aged adults at cardiometabolic risk: a randomised controlled trial.Open heart · 2026Trial
- Strategic daytime napping enhances agility and lowers perceived exertion but does not improve fatigue resistance in adolescent soccer players.Scientific reports · 2026Trial
- Effects of chronotype-tailored bright light intervention on post-treatment symptoms and quality of life in breast cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Trial
- Association between circadian rhythm-related behaviors and breast cancer: a bidirectional Mendelian randomization study.Future science OA · 2026Article
- BMAL1 Dysregulation as a Contributing Mechanism Linking Obesity to Oocyte and Endometrial Dysfunction in IVF.International journal of molecular sciences · 2026Review
- The Influence of Time of Day on Critical Swimming Speed in Chronotype-Screened (Neither-Type) Well-Trained Male Swimmers.Life (Basel, Switzerland) · 2026Article
- Social jetlag and academic performance in adolescents: insights from a region with structural circadian misalignment.European journal of pediatrics · 2026Article
- Reference Genes for Circadian Profiling of Core Clock Genes in the Blood of Obstructive Sleep Apnea Patients.Biomolecules · 2026Article
- Therapeutic prospects of bright light therapy in addictive disorders: a scoping review.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Sleep and Circadian Rhythms in Patients with Physical and Mental Disorders.Journal of clinical medicine · 2026Article
99 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The circadian rhythm plays a fundamental role in regulating biological functions, including sleep-wake preference, body temperature, hormonal secretion, food intake, and cognitive and physical performance. Alterations in circadian rhythm can lead to chronic disease and impaired sleep. The circadian rhythmicity in human beings is represented by a complex phenotype. Indeed, over a 24-h period, a person's preferred time to be more active or to sleep can be expressed in the concept of morningness-eveningness. Three chronotypes are distinguished: Morning, Neither, and Evening-types. Interindividual differences in chronotypes need to be considered to reduce the negative effects of circadian disruptions on health. In the present review, we examine the bi-directional influences of the rest-activity circadian rhythm and sleep-wake cycle in chronic pathologies and disorders. We analyze the concept and the main characteristics of the three chronotypes.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.