Evidence map›Paper›PMID 33804924›Full record

ArticlePharmaceutics2021

Changes in Skin Barrier Function after Repeated Exposition to Phospholipid-Based Surfactants and Sodium Dodecyl Sulfate In Vivo and Corneocyte Surface Analysis by Atomic Force Microscopy.

Claudia Vater, Alexandra Apanovic, Christoph Riethmüller, Brigitte Litschauer, Michael Wolzt, Claudia Valenta, Victoria Klang

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. TotalInternational journal of molecular sciences · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Characterization and ex vivo evaluation of excised skin samples as substitutes for human dermal barrier in pharmaceutical and dermatological studies.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2022
    Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Claudia VaterDepartment of Pharmaceutical Technology and Biopharmaceutics, Faculty of Life Sciences, University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-5377-657X
Alexandra ApanovicDepartment of Pharmaceutical Technology and Biopharmaceutics, Faculty of Life Sciences, University of Vienna, 1090 Vienna, Austria.
Christoph RiethmüllerSerend-ip GmbH, Centre for Nanotechnology, 48149 Münster, Germany.
Brigitte LitschauerDepartment of Clinical Pharmacology, Medical University of Vienna, 1090 Vienna, Austria.
Michael WolztDepartment of Clinical Pharmacology, Medical University of Vienna, 1090 Vienna, Austria.
Claudia ValentaDepartment of Pharmaceutical Technology and Biopharmaceutics, Faculty of Life Sciences, University of Vienna, 1090 Vienna, Austria.
Victoria KlangDepartment of Pharmaceutical Technology and Biopharmaceutics, Faculty of Life Sciences, University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-2561-4378
University of Vienna · ATMedical University of Vienna · ATCeNTech · DE

Funding

Phospholipid Research Center CVA-2018-063/2-1
6 · The paper itself

Abstract

(1) Background: The aim of the study was to evaluate the effect of pure lecithins in comparison to a conventional surfactant on skin in vivo. (2) Methods: Physiological skin parameters were evaluated at the beginning and the end of the study (day 1 and day 4) (

Indexed as

atomic force microscopycorneocytesdermal texture indexlecithinsnatural moisturizing factorphospholipidsskin hydrationsodium dodecyl sulfatesurfactantstransepidermal water loss

Identifiers

PMID33804924
PMCPMC8063842
OpenAlexW3136594213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.