Evidence map›Paper›PMID 33804909›Full record

ReviewNutrients2021

The Role of Oat Nutrients in the Immune System: A Narrative Review.

Oliver Chen, Eunice Mah, ElHadji Dioum, Ankita Marwaha, Shobana Shanmugam, Nagappa Malleshi, Vasudevan Sudha, Rajagopal Gayathri, Ranjit Unnikrishnan, Ranjit Mohan Anjana and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Neiyou 6, a high yielding and high β-glucan hulless oat variety.Molecular breeding : new strategies in plant improvement · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Changes in Plant and Grain Quality of Winter Oat (Plants (Basel, Switzerland) · 2023
    Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Genetic diversity in nutritional composition of oat (Saudi journal of biological sciences · 2022
    Article
  18. Article
  19. Mushrooms as future generation healthy foods.Frontiers in nutrition · 2022
    Review
  20. Frontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Oliver ChenBiofortis Research, Mérieux NutriSciences, Addison, IL 60101, USA.ORCID 0000-0002-6273-9017
Eunice MahBiofortis Research, Mérieux NutriSciences, Addison, IL 60101, USA.
ElHadji DioumQuaker Oats Center of Excellence, PepsiCo Health & Nutrition Sciences, Barrington, IL 60010, USA.
Ankita MarwahaPepsiCo Health & Nutrition Sciences, AMESA, Gurgaon 122101, India.
Shobana ShanmugamMadras Diabetes Research Foundation, Chennai, Tamil Nadu 600086, India.
Nagappa MalleshiMadras Diabetes Research Foundation, Chennai, Tamil Nadu 600086, India.
Vasudevan SudhaMadras Diabetes Research Foundation, Chennai, Tamil Nadu 600086, India.
Rajagopal GayathriMadras Diabetes Research Foundation, Chennai, Tamil Nadu 600086, India.
Ranjit UnnikrishnanMadras Diabetes Research Foundation, Chennai, Tamil Nadu 600086, India.
Ranjit Mohan AnjanaMadras Diabetes Research Foundation, Chennai, Tamil Nadu 600086, India.
Kamala KrishnaswamyMadras Diabetes Research Foundation, Chennai, Tamil Nadu 600086, India.
Viswanathan MohanMadras Diabetes Research Foundation, Chennai, Tamil Nadu 600086, India.
YiFang ChuQuaker Oats Center of Excellence, PepsiCo Health & Nutrition Sciences, Barrington, IL 60010, USA.
Madras Diabetes Research Foundation · INPepsi (United States) · USPepsiCo (India) · INTufts University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optimal nutrition is the foundation for the development and maintenance of a healthy immune system. An optimal supply of nutrients is required for biosynthesis of immune factors and immune cell proliferation. Nutrient deficiency/inadequacy and hidden hunger, which manifests as depleted nutrients reserves, increase the risk of infectious diseases and aggravate disease severity. Therefore, an adequate and balanced diet containing an abundant diversity of foods, nutrients, and non-nutrient chemicals is paramount for an optimal immune defense against infectious diseases, including cold/flu and non-communicable diseases. Some nutrients and foods play a larger role than others in the support of the immune system. Oats are a nutritious whole grain and contain several immunomodulating nutrients. In this narrative review, we discuss the contribution of oat nutrients, including dietary fiber (β-glucans), copper, iron, selenium, and zinc, polyphenolics (ferulic acid and avenanthramides), and proteins (glutamine) in optimizing the innate and adaptive immune system's response to infections directly by modulating the innate and adaptive immunity and indirectly by eliciting changes in the gut microbiota and related metabolites.

Indexed as

AvenaDietDietary FiberHumansImmunityNutrientsDietary FiberNutrientsfiberhumanmineralspolyphenolsprotein

Identifiers

PMID33804909
PMCPMC8063794
OpenAlexW3144105323

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.