Evidence map›Paper›PMID 33804841›Full record

ArticleCells2021

Assessment of the Neuroprotective and Stemness Properties of Human Wharton's Jelly-Derived Mesenchymal Stem Cells under Variable (5% vs. 21%) Aerobic Conditions.

Ewelina Tomecka, Wioletta Lech, Marzena Zychowicz, Anna Sarnowska, Magdalena Murzyn, Tomasz Oldak, Krystyna Domanska-Janik, Leonora Buzanska, Natalia Rozwadowska

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ewelina TomeckaPolish Stem Cell Bank, FamiCord Group, 00-867 Warsaw, Poland.
Wioletta LechDepartment of Stem Cell Bioengineering, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.ORCID 0000-0002-5634-2224
Marzena ZychowiczDepartment of Stem Cell Bioengineering, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.ORCID 0000-0002-3145-3059
Anna SarnowskaDepartment of Stem Cell Bioengineering, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.ORCID 0000-0001-6974-8592
Magdalena MurzynPolish Stem Cell Bank, FamiCord Group, 00-867 Warsaw, Poland.
Tomasz OldakPolish Stem Cell Bank, FamiCord Group, 00-867 Warsaw, Poland.
Krystyna Domanska-JanikDepartment of Stem Cell Bioengineering, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.
Leonora BuzanskaDepartment of Stem Cell Bioengineering, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.ORCID 0000-0003-4433-9906
Natalia RozwadowskaInstitute of Human Genetics, Polish Academy of Sciences, 60-479 Poznan, Poland.ORCID 0000-0002-5111-0870
Mossakowski Medical Research Institute, Polish Academy of Sciences · PLPolish Stem Cell Bank · PLInstitute of Human Genetics · PL

Funding

Ministerstwo Nauki i Szkolnictwa Wyższego DWD/3/27/2019MMRI PAS Statutury fundsNarodowe Centrum Badań i Rozwoju No. POIR.01.02.00-00-00024/17-00
6 · The paper itself

Abstract

To optimise the culture conditions for human Wharton's jelly-derived mesenchymal stem cells (hWJ-MSCs) intended for clinical use, we investigated ten different properties of these cells cultured under 21% (atmospheric) and 5% (physiological normoxia) oxygen concentrations. The obtained results indicate that 5% O

Indexed as

NeuroprotectionCell DifferentiationCell LineageCell ProliferationCells, CulturedCell ShapeCellular SenescenceClone CellsHumansImmunophenotypingMesenchymal Stem CellsNeuronsNeuroprotective AgentsOxygenWharton JellyNeuroprotective AgentsOxygenneuroprotectionoxygen conditionssecretory profileumbilical cordWharton’s jelly mesenchymal stem cells

Identifiers

PMID33804841
PMCPMC8063843
OpenAlexW3138987426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.