SynthesisViruses2021
Dengue Virus Infection and Associated Risk Factors in Africa: A Systematic Review and Meta-Analysis.
Synthesis in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- The magnitude of flaviviruses infection in Ethiopia: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Quantitative modelling for dengue and Aedes mosquitoes in Africa: A systematic review of current approaches and future directions for Early Warning System development.PLoS neglected tropical diseases · 2024Pooled it
- Seroprevalence of seven arboviruses of public health importance in sub-Saharan Africa: a systematic review and meta-analysis.BMJ global health · 2024Pooled it
- A dengue virus infection in Ethiopia: a systematic review and meta-analysis.BMC infectious diseases · 2024Pooled it
- A decade of dengue disease burden in Africa (2013-2023): a systematic review.Travel medicine and infectious diseasePooled it
- Dengue virus infection in Saudi Arabia from 2003 to 2023: a systematic review and meta-analysis.Pathogens and global healthPooled it
- Mapping mosquitoes and their associated pathogens in West Africa.Infectious diseases of poverty · 2026Article
- Molecular and Serological Surveillance of Dengue Virus and Vector Dynamics in the Highlands of Southwestern Saudi Arabia.Current microbiology · 2026Article
- Dengue and chikungunya virus transmission in Kinshasa, Democratic Republic of the Congo.medRxiv : the preprint server for health sciences · 2026Article
- Prevalence and Risk Factors of Dengue Virus Infection Among Febrile Patients in a Malaria Hyperendemic Area of Southern Mali.Research square · 2026Article
- Spatiotemporal dynamics of dengue: a town level study in Guangdong, China.BMC infectious diseases · 2026Article
- Contrasting egg-laying, adult abundance and genetics of the dengue vector Aedes aegypti in two ecologically distinct regions in Kenya.Tropical medicine and health · 2026Article
- Outbreak of dengue fever in Ghana: The emergence of DENV-1 serotype.PLoS neglected tropical diseases · 2026Article
- Establishment of multiple predictive models for early identification of the dengue cases in outpatient healthcare systems.Scientific reports · 2026Article
- (Sero)prevalence of (re)emerging major arbovirus infections in Africa: a systematic review and meta-analysis protocol.Systematic reviews · 2026Article
- Entomo-virological investigation in urban forest fragments and intradomiciles during a dengue outbreak in Salinas, MG, Brazil.Memorias do Instituto Oswaldo Cruz · 2026Article
- Evolutionary history and transmission dynamics of dengue virus type 2 in Africa.Frontiers in microbiology · 2026Article
- Dengue diagnosis in Guinea in two returning travelers from Côte d'Ivoire: a case report.IJID regions · 2025Article
- A Systematic Review and Meta-Analysis of Maternal Dengue Infection and Adverse Pregnancy Outcomes.Cureus · 2025Review
- Risk factors associated with dengue and chikungunya seroprevalence and seroconversion among urban populations in western and coastal Kenya.PLoS neglected tropical diseases · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dengue contributes a significant burden on global public health and economies. In Africa, the burden of dengue virus (DENV) infection is not well described. This review was undertaken to determine the prevalence of dengue and associated risk factors. A literature search was done on PubMed/MEDLINE, Scopus, Embase, and Google Scholar databases to identify articles published between 1960 and 2020. Meta-analysis was performed using a random-effect model at a 95% confidence interval, followed by subgroup meta-analysis to determine the overall prevalence. Between 1960 and 2020, 45 outbreaks were identified, of which 17 and 16 occurred in East and West Africa, respectively. Dengue virus serotype 1 (DENV-1) and DENV-2 were the dominant serotypes contributing to 60% of the epidemics. Of 2211 cases reported between 2009 and 2020; 1954 (88.4%) were reported during outbreaks. Overall, the prevalence of dengue was 29% (95% CI: 20-39%) and 3% (95% CI: 1-5%) during the outbreak and non-outbreak periods, respectively. Old age (6/21 studies), lack of mosquito control (6/21), urban residence (4/21), climate change (3/21), and recent history of travel (3/21) were the leading risk factors. This review reports a high burden of dengue and increased risk of severe disease in Africa. Our findings provide useful information for clinical practice and health policy decisions to implement effective interventions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.