Evidence map›Paper›PMID 33804830›Full record

ReviewBiology2021

The Zebrafish Xenograft Models for Investigating Cancer and Cancer Therapeutics.

John T Gamble, Daniel J Elson, Juliet A Greenwood, Robyn L Tanguay, Siva K Kolluri

Abstract readReview
In one paragraph

Review in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Glioblastoma research on zebrafish xenograft models: a systematic review.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Pooled it
  2. Review
  3. Review
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  5. Article
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  7. Targeting platelet-tumor cell interactions via thromboxane AExperimental hematology & oncology · 2025
    Article
  8. Review
  9. Review
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  11. Antitumor Activity ofMarine drugs · 2025
    Article
  12. Article
  13. Review
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  15. Article
  16. Article
  17. Review
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  19. Zebrafish live imaging: a strong weapon in anticancer drug discovery and development.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

John T GambleDepartment of Biochemistry & Biophysics, Oregon State University, Corvallis, OR 97331, USA.
Daniel J ElsonCancer Research Laboratory, Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR 97331, USA.ORCID 0000-0001-9528-0970
Juliet A GreenwoodSchool of Mathematics and Natural Sciences, Arizona State University, Scotsdale, AZ 85257, USA.
Robyn L TanguayDepartment of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR 97331, USA.ORCID 0000-0001-6190-3682
Siva K KolluriCancer Research Laboratory, Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR 97331, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to develop new cancer therapeutics, rapid, reliable, and relevant biological models are required to screen and validate drug candidates for both efficacy and safety. In recent years, the zebrafish (

Indexed as

cancer therapeuticsdrug discoverydrug screeningtoxicity testingxenograftzebrafish

Identifiers

PMID33804830
PMCPMC8063817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.