Evidence map›Paper›PMID 33804823›Full record

ReviewBiology2021

A Review of Genetic Abnormalities in Unicentric and Multicentric Castleman Disease.

Alexandra Butzmann, Jyoti Kumar, Kaushik Sridhar, Sumanth Gollapudi, Robert S Ohgami

Open access · goldAbstract readReview
In one paragraph

Review in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. TAFRO Syndrome and COVID-19.Biomedicines · 2024
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. International definition of iMCD-TAFRO: future perspectives.Journal of clinical and experimental hematopathology : JCEH · 2022
    Article
  14. Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Alexandra ButzmannAgilent Technologies, Santa Clara, CA 95051, USA.
Jyoti KumarDepartment of Pathology, Stanford University, Stanford, CA 94305, USA.
Kaushik SridharDepartment of Pathology, University of California, San Francisco, CA 94143, USA.
Sumanth GollapudiDepartment of Pathology, University of California, San Francisco, CA 94143, USA.ORCID 0000-0002-5302-3420
Robert S OhgamiDepartment of Pathology, University of California, San Francisco, CA 94143, USA.
University of California, San Francisco · USAgilent Technologies (United States) · USStanford University · US

Funding

University of Pennsylvania MDBR-18-105-Castleman
6 · The paper itself

Abstract

Castleman disease (CD) is a rare lymphoproliferative disorder known to represent at least four distinct clinicopathologic subtypes. Large advancements in our clinical and histopathologic description of these diverse diseases have been made, resulting in subtyping based on number of enlarged lymph nodes (unicentric versus multicentric), according to viral infection by human herpes virus 8 (HHV-8) and human immunodeficiency virus (HIV), and with relation to clonal plasma cells (POEMS). In recent years, significant molecular and genetic abnormalities associated with CD have been described. However, we continue to lack a foundational understanding of the biological mechanisms driving this disease process. Here, we review all cases of CD with molecular abnormalities described in the literature to date, and correlate cytogenetic, molecular, and genetic abnormalities with disease subtypes and phenotypes. Our review notes complex karyotypes in subsets of cases, specific mutations in

Indexed as

Castleman diseasemulticentric Castleman diseasePOEMS syndromeTAFRO syndromeunicentric Castleman disease

Identifiers

PMID33804823
PMCPMC8063830
OpenAlexW3139272951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.