Evidence map›Paper›PMID 33804780›Full record

ArticleJournal of fungi (Basel, Switzerland)2021

In Vitro Activity of Ibrexafungerp against a Collection of Clinical Isolates of

Olga Rivero-Menendez, Juan Carlos Soto-Debran, Manuel Cuenca-Estrella, Ana Alastruey-Izquierdo

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Pathogenesis and Triazole Resistance inInfection and drug resistance · 2026
    Review
  7. Azole-ResistantJournal of fungi (Basel, Switzerland) · 2025
    Review
  8. Antimicrobial agents and chemotherapy · 2025
    Article
  9. Review
  10. Review
  11. Ibrexafungerp: A narrative overview.Current research in microbial sciences · 2024
    Review
  12. Review
  13. Invasive Pulmonary Aspergillosis.Journal of fungi (Basel, Switzerland) · 2023
    Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Antifungal Resistance and the Role of New Therapeutic Agents.Current infectious disease reports · 2022
    Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Olga Rivero-MenendezNational Centre for Microbiology, Mycology Reference Laboratory, Instituto de Salud Carlos III, 28222 Madrid, Spain.
Juan Carlos Soto-DebranNational Centre for Microbiology, Mycology Reference Laboratory, Instituto de Salud Carlos III, 28222 Madrid, Spain.
Manuel Cuenca-EstrellaNational Centre for Microbiology, Mycology Reference Laboratory, Instituto de Salud Carlos III, 28222 Madrid, Spain.
Ana Alastruey-IzquierdoNational Centre for Microbiology, Mycology Reference Laboratory, Instituto de Salud Carlos III, 28222 Madrid, Spain.ORCID 0000-0001-8651-4405
Instituto de Salud Carlos III · ES

Funding

Instituto de Salud Carlos III FI14CIII/00025Scynexis Inc. N
6 · The paper itself

Abstract

Ibrexafungerp is a new orally-available 1,3-β-D-glucan synthesis inhibitor in clinical development. Its in vitro activity and that of amphotericin B, voriconazole, and micafungin were evaluated against a collection of 168 clinical isolates of

Indexed as

antifungalsAspergillusCLSIcrypticcyp51AEUCASTibrexafungerp

Identifiers

PMID33804780
PMCPMC8003840
OpenAlexW3137547661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.