Evidence map›Paper›PMID 33804762›Full record

ArticleJournal of clinical medicine2021

Lung Ultrasound Patterns and Clinical-Laboratory Correlates during COVID-19 Pneumonia: A Retrospective Study from North East Italy.

Riccardo Senter, Federico Capone, Stefano Pasqualin, Lorenzo Cerruti, Leonardo Molinari, Elisa Fonte Basso, Nicolò Zanforlin, Lorenzo Previato, Alessandro Toffolon, Caterina Sensi and 24 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  4. New International Guidelines and Consensus on the Use of Lung Ultrasound.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors at 2 institutions in 1 country.

Riccardo SenterDepartment of Medicine, University of Padova, Via VIII Febbraio, 2, 35122 Padova, Italy.ORCID 0000-0001-7987-8235
Federico CaponeDepartment of Medicine, University of Padova, Via VIII Febbraio, 2, 35122 Padova, Italy.ORCID 0000-0001-8127-5564
Stefano PasqualinDepartment of Emergency, University Hospital of Padova, Via Giustiniani, 2, 35128 Padova, Italy.
Lorenzo CerrutiDepartment of Medicine, University of Padova, Via VIII Febbraio, 2, 35122 Padova, Italy.
Leonardo MolinariDepartment of Medicine, University of Padova, Via VIII Febbraio, 2, 35122 Padova, Italy.ORCID 0000-0002-2428-383X
Elisa Fonte BassoDepartment of Emergency, University Hospital of Padova, Via Giustiniani, 2, 35128 Padova, Italy.ORCID 0000-0001-6440-837X
Nicolò ZanforlinDepartment of Emergency, University Hospital of Padova, Via Giustiniani, 2, 35128 Padova, Italy.
Lorenzo PreviatoDepartment of Medicine, University of Padova, Via VIII Febbraio, 2, 35122 Padova, Italy.
Alessandro ToffolonDepartment of Medicine, University of Padova, Via VIII Febbraio, 2, 35122 Padova, Italy.
Caterina SensiDepartment of Medicine, University of Padova, Via VIII Febbraio, 2, 35122 Padova, Italy.ORCID 0000-0002-2136-3906
Gaetano ArcidiaconoDepartment of Medicine, University of Padova, Via VIII Febbraio, 2, 35122 Padova, Italy.ORCID 0000-0003-0409-4449
Davide GorgiDepartment of Medicine, University of Padova, Via VIII Febbraio, 2, 35122 Padova, Italy.ORCID 0000-0002-9190-7585
Renato IppolitoDepartment of Emergency, University Hospital of Padova, Via Giustiniani, 2, 35128 Padova, Italy.ORCID 0000-0003-1194-3023
Enrico NessiDepartment of Emergency, University Hospital of Padova, Via Giustiniani, 2, 35128 Padova, Italy.
Pietro PettenellaDepartment of Emergency, University Hospital of Padova, Via Giustiniani, 2, 35128 Padova, Italy.
Andrea CelliniDepartment of Emergency, University Hospital of Padova, Via Giustiniani, 2, 35128 Padova, Italy.
Claudio FossaDepartment of Emergency, University Hospital of Padova, Via Giustiniani, 2, 35128 Padova, Italy.
Eleonora VaniaDepartment of Emergency, University Hospital of Padova, Via Giustiniani, 2, 35128 Padova, Italy.ORCID 0000-0002-5295-3087
Samuele GardinDepartment of Infectious Diseases, University Hospital of Padova, Via Giustiniani, 2, 35128 Padova, Italy.
Andi SukthiDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy.
Dora LuiseInfectious and Tropical Diseases, San Bortolo Hospital, Viale Rodolfi, 37, 36100 Vicenza, Italy.
Maria Teresa GiordaniInfectious and Tropical Diseases, San Bortolo Hospital, Viale Rodolfi, 37, 36100 Vicenza, Italy.
Mirko ZanattaDepartment of Emergency, Arzignano Hospital, Via del Parco, 1, 36071 Arzignano, Italy.
Sandro SavinoDepartment of Medicine, University of Padova, Via VIII Febbraio, 2, 35122 Padova, Italy.ORCID 0000-0003-0184-7580
Vito CianciDepartment of Emergency, University Hospital of Padova, Via Giustiniani, 2, 35128 Padova, Italy.
Andrea SattinDepartment of Infectious Diseases, University Hospital of Padova, Via Giustiniani, 2, 35128 Padova, Italy.
Anna MariaDepartment of Infectious Diseases, University Hospital of Padova, Via Giustiniani, 2, 35128 Padova, Italy.ORCID 0000-0003-2869-2945
Andrea VianelloDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy.ORCID 0000-0002-8790-6029
Raffaele PesaventoInternal Medicine, Montebelluna Hospital, Via Palmiro Togliatti, 1, 31044 Montebelluna, Italy.
Sandro GianniniDepartment of Medicine, University of Padova, Via VIII Febbraio, 2, 35122 Padova, Italy.ORCID 0000-0003-0796-9749
Angelo AvogaroDepartment of Medicine, University of Padova, Via VIII Febbraio, 2, 35122 Padova, Italy.ORCID 0000-0002-1177-0516
Roberto VettorDepartment of Medicine, University of Padova, Via VIII Febbraio, 2, 35122 Padova, Italy.
Gian Paolo FadiniDepartment of Medicine, University of Padova, Via VIII Febbraio, 2, 35122 Padova, Italy.ORCID 0000-0002-6510-2097
Alois SallerDepartment of Medicine, University of Padova, Via VIII Febbraio, 2, 35122 Padova, Italy.
University of Padua · ITOspedale San Bortolo · IT

Funding

Fondazione Cassa di Risparmio di Padova e Rovigo COVIDIMED
6 · The paper itself

Abstract

BACKGROUND AND

aimLung ultrasound (LUS) is a convenient imaging modality in the setting of coronavirus disease-19 (COVID-19) because it is easily available, can be performed bedside and repeated over time. We herein examined LUS patterns in relation to disease severity and disease stage among patients with COVID-19 pneumonia.

methodsWe performed a retrospective case series analysis of patients with confirmed SARS-CoV-2 infection who were admitted to the hospital because of pneumonia. We recorded history, clinical parameters and medications. LUS was performed and scored in a standardized fashion by experienced operators, with evaluation of up to 12 lung fields, reporting especially on B-lines and consolidations.

resultsWe included 96 patients, 58.3% men, with a mean age of 65.9 years. Patients with a high-risk quick COVID-19 severity index (qCSI) were older and had worse outcomes, especially for the need for high-flow oxygen. B-lines and consolidations were located mainly in the lower posterior lung fields. LUS patterns for B-lines and consolidations were significantly worse in all lung fields among patients with high versus low qCSI. B-lines and consolidations were worse in the intermediate disease stage, from day 7 to 13 after onset of symptoms. While consolidations correlated more with inflammatory biomarkers, B-lines correlated more with end-organ damage, including extrapulmonary involvement.

conclusionsLUS patterns provide a comprehensive evaluation of patients with COVID-19 pneumonia that correlated with severity and dynamically reflect disease stage. LUS patterns may reflect different pathophysiological processes related to inflammation or tissue damage; consolidations may represent a more specific sign of localized disease, whereas B-lines seem to be also dependent upon generalized illness due to SARS-CoV-2 infection.

Indexed as

B-linesconsolidationsCOVID-19lung ultrasound

Identifiers

PMID33804762
PMCPMC8004000
OpenAlexW3136294350

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.