ReviewBrain sciences2021
Processing of Degraded Speech in Brain Disorders.
Review in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 21 citations in OpenAlex.
- Speech-In-Noise Perception in Alzheimer's Disease and Primary Progressive Aphasia.European journal of neurology · 2026Article
- Cluttering in Children and Adolescents: Speech Motor Development, Neurocognitive Mechanisms, and Allied Health Implications.Children (Basel, Switzerland) · 2026Review
- Article
- Comprehension of acoustically degraded emotional prosody in Alzheimer's disease and primary progressive aphasia.Scientific reports · 2024Article
- Primary progressive aphasia: six questions in search of an answer.Journal of neurology · 2024Review
- Symptom-led staging for semantic and non-fluent/agrammatic variants of primary progressive aphasia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Comprehension of acoustically degraded speech in Alzheimer's disease and primary progressive aphasia.Brain : a journal of neurology · 2023Article
- Symptom-led staging for primary progressive aphasia.medRxiv : the preprint server for health sciences · 2023Article
- Article
- Phonemic restoration in Alzheimer's disease and semantic dementia: a preliminary investigation.Brain communications · 2022Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
The speech we hear every day is typically "degraded" by competing sounds and the idiosyncratic vocal characteristics of individual speakers. While the comprehension of "degraded" speech is normally automatic, it depends on dynamic and adaptive processing across distributed neural networks. This presents the brain with an immense computational challenge, making degraded speech processing vulnerable to a range of brain disorders. Therefore, it is likely to be a sensitive marker of neural circuit dysfunction and an index of retained neural plasticity. Considering experimental methods for studying degraded speech and factors that affect its processing in healthy individuals, we review the evidence for altered degraded speech processing in major neurodegenerative diseases, traumatic brain injury and stroke. We develop a predictive coding framework for understanding deficits of degraded speech processing in these disorders, focussing on the "language-led dementias"-the primary progressive aphasias. We conclude by considering prospects for using degraded speech as a probe of language network pathophysiology, a diagnostic tool and a target for therapeutic intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.