Evidence map›Paper›PMID 33804603›Full record

ReviewNutrients2021

Ketogenic Diet as a Preventive and Supportive Care for COVID-19 Patients.

Elena Gangitano, Rossella Tozzi, Orietta Gandini, Mikiko Watanabe, Sabrina Basciani, Stefania Mariani, Andrea Lenzi, Lucio Gnessi, Carla Lubrano

Abstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. How Food Choices Impact on Male Fertility.Current nutrition reports · 2023
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  14. Role of senescence in the chronic health consequences of COVID-19.Translational research : the journal of laboratory and clinical medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elena GangitanoDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0003-1044-2278
Rossella TozziDepartment of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-3358-4204
Orietta GandiniDepartment of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-7867-1010
Mikiko WatanabeDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0003-2225-8814
Sabrina BascianiDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Stefania MarianiDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0003-1762-4701
Andrea LenziDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Lucio GnessiDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Carla LubranoDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-8261-1451

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe obesity is associated with an increased risk of admission to intensive care units and need for invasive mechanical ventilation in patients with COVID-19. The association of obesity and COVID-19 prognosis may be related to many different factors, such as chronic systemic inflammation, the predisposition to severe respiratory conditions and viral infections. The ketogenic diet is an approach that can be extremely effective in reducing body weight and visceral fat in the short term, preserving the lean mass and reducing systemic inflammation. Therefore, it is a precious preventive measure for severely obese people and may be considered as an adjuvant therapy for patients with respiratory compromise.

Indexed as

COVID-19Diet, KetogenicHumansInflammationObesityRespiratory SystemCOVID-19inflammationketogenic dietobesityrespiratory failureSARS-CoV-2viral infectionsVLCKD

Identifiers

PMID33804603
PMCPMC8003632

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.