ReviewBiology2021
Dietary Antioxidants in the Treatment of Male Infertility: Counteracting Oxidative Stress.
Review in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Protective effects of melatonin against physical injuries to testicular tissue: A systematic review and meta-analysis of animal models.Frontiers in endocrinology · 2023Pooled it
- Vitamin D3 Supplementation Effects on Spermatogram and Oxidative Stress Biomarkers in Asthenozoospermia Infertile Men: a Randomized, Triple-Blind, Placebo-Controlled Clinical Trial.Reproductive sciences (Thousand Oaks, Calif.) · 2022Trial
- Metabolic Syndrome and Male Infertility: The Role of Obesity and Chronic Inflammation.Biomedicines · 2026Review
- Impact of A Fertility Diet on Male Reproductive Function: A 12-Week Randomized Clinical Trial in Idiopathic Infertility Patients.International journal of fertility & sterility · 2026Article
- Nutritional modulation of male fertility: a molecular-focused scoping review.Journal of health, population, and nutrition · 2026Article
- Sixty-day oral antioxidant supplementation enhances sperm morphology and seminal plasma antioxidant capacity in stallions.Journal of animal science · 2026Article
- Protective effects of royal jelly on testicular tissue damage in rats treated with methotrexate: the relationship between oxidative stress and autophagy.Veterinary research forum : an international quarterly journal · 2026Article
- Nutritional modulation of the gut-reproductive axis: multi-strain probiotic blend on oxidative and seminal parameters in healthy male dogs.Frontiers in veterinary science · 2026Article
- Effect of patient and partner preconceptional nutraceutical supplementation on the onset of natural pregnancy: a retrospective study.Revista da Associacao Medica Brasileira (1992) · 2026Article
- The role of oxidative stress in sleep deprivation-induced reproductive dysfunction: A rationale for anti-oxidant intervention.Iranian journal of basic medical sciences · 2026Review
- Dietary antioxidants and micronutrient status in varicocele-associated male infertility: oxidative stress-mediated effects on semen quality.Frontiers in nutrition · 2026Article
- Reductive stress and the role of antioxidants in male infertility: a narrative review.Archives of gynecology and obstetrics · 2025Review
- The aging male: impact of aging on male reproduction.Biogerontology · 2025Review
- Nutrition and Diet in the Prevention and Management of Prostate Cancer in Mexico: A Narrative Review.Nutrients · 2025Review
- The association of global and prime diet quality scores with sperm quality parameters: a cross-sectional study.Journal of health, population, and nutrition · 2025Article
- Comparing the Effectiveness of Expressive Writing and Relaxation on Mental Health and Treatment Success in Women Undergoing Assisted Reproductive Technology: A Randomized Controlled Trial.Journal of family & reproductive health · 2025Article
- Sweet Drinks, Sour Consequences: The Impact of Sugar-Sweetened Beverages on Sperm Health, a Narrative Review.Nutrients · 2025Review
- Survey of tocopherol and the associated genetic loci in wheat grain.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Review
- Lycopene in male infertility.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- From Inflammation to Infertility: How Oxidative Stress and Infections Disrupt Male Reproductive Health.Metabolites · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infertility affects about 15% of the population and male factors only are responsible for ~25-30% of cases of infertility. Currently, the etiology of suboptimal semen quality is poorly understood, and many environmental and genetic factors, including oxidative stress, have been implicated. Oxidative stress is an imbalance between the production of free radicals, or reactive oxygen species (ROS), and the capacity of the body to counteract their harmful effects through neutralization by antioxidants. The purpose of this review, by employing the joint expertise of international researchers specialized in nutrition and male fertility areas, is to update the knowledge about the reproductive consequences of excessive ROS concentrations and oxidative stress on the semen quality and Assisted Reproduction Techniques (ART) clinical outcomes, to discuss the role of antioxidants in fertility outcomes, and finally to discuss why foods and dietary patterns are more innocuous long term solution for ameliorating oxidative stress and therefore semen quality results and ART fertility outcomes. Since this is a narrative review and not a systematic/meta-analysis, the summarized information in the present study should be considered cautiously.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.