Evidence map›Paper›PMID 33804585›Full record

ArticleCancers2021

The Potential of Colonic Tumor Tissue

Pamela Pignatelli, Lorena Iezzi, Martina Pennese, Paolo Raimondi, Anna Cichella, Danilo Bondi, Rossella Grande, Roberto Cotellese, Nicola Di Bartolomeo, Paolo Innocenti and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. NO: a key player in microbiome dynamics and cancer pathogenesis.Frontiers in cellular and infection microbiology · 2025
    Review
  6. Article
  7. IntratumoralPathogens (Basel, Switzerland) · 2024
    Review
  8. Article
  9. Review
  10. Review
  11. The Immune System Response toMicroorganisms · 2023
    Article
  12. The Role ofMicroorganisms · 2023
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Journal of Cancer · 2023
    Article
  18. Review
  19. The Role ofCancers · 2022
    Review
  20. OralBiomedicines · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Pamela PignatelliDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy.ORCID 0000-0002-3023-7143
Lorena IezziDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy.
Martina PenneseDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy.
Paolo RaimondiDepartment of General Surgery, Private Hospital "Villa Serena", Città Sant'Angelo, 65013 Pescara, Italy.
Anna CichellaDepartment of General Surgery, Private Hospital "Villa Serena", Città Sant'Angelo, 65013 Pescara, Italy.
Danilo BondiDepartment of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy.ORCID 0000-0003-1911-3606
Rossella GrandeDepartment of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy.ORCID 0000-0002-8432-6889
Roberto CotelleseDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy.
Nicola Di BartolomeoDepartment of General Surgery, Private Hospital "Villa Serena", Città Sant'Angelo, 65013 Pescara, Italy.
Paolo InnocentiDepartment of General Surgery, Private Hospital "Villa Serena", Città Sant'Angelo, 65013 Pescara, Italy.
Adriano PiattelliDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy.
Maria Cristina CuriaDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy.
University of Chieti-Pescara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntestinal microbiota dysbiosis may enhance the carcinogenicity of colon cancer (CC) by the proliferation and differentiation of epithelial cells. Oral

methodsThirty-six CC patients were included in the study to assess the

resultsPatients had a greater quantity of

conclusionIn our study,

Indexed as

abundancecolon cancerdietdysbiosisFusobacterium nucleatumlifestyleoral microbiotaPorphyromonas gingivalisstagingtumor microenvironment

Identifiers

PMID33804585
PMCPMC7957509
OpenAlexW3133965319

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.