ArticleCancers2021
Surgical Management of Sporadic Peripheral Nerve Schwannomas in Adults: Indications and Outcome in a Single Center Cohort.
Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Management of an Intralingual Ancient Schwannoma.Cureus · 2026Article
- Predictive factors with the growth of remnant tumor after incomplete resection of thoracic dumbbell-shaped schwannomas.Spinal cord · 2026Article
- Multidisciplinary Management of an Atypical Gigantic Sciatic Nerve Schwannoma: Case Presentation and Systematic Review.NeuroSci · 2025Article
- Gastrointestinal schwannomas: A case series of 9 patients and literature review.Turkish journal of surgery · 2025Article
- Intramuscular schwannoma presenting as treatment-resistant lumbar radiculopathy: Case report.Interventional pain medicine · 2025Article
- Article
- Segmental resection of myxoid chondrosarcoma: a case report.Frontiers in oncology · 2025Article
- Perioperative Observations and Outcome in Surgical Treatment of Malignant Peripheral Nerve Sheath Tumors.Cancers · 2024Article
- MRI features of benign peripheral nerve sheath tumors: how do sporadic and syndromic tumors differ?Skeletal radiology · 2024Article
- Case report: Solitary mass of the sciatic nerve confirmed as a primary extranodal manifestation of diffuse large B-cell lymphoma in a geriatric patient.Frontiers in oncology · 2024Article
- Review
- Management of neurofibromatosis type 2 and schwannomatosis associated peripheral and intraspinal schwannomas: influence of surgery, genetics, and localization.Journal of neuro-oncology · 2022Observational
- Axillary schwannoma mimicking lymph node metastasis-associated breast cancer: a case report.Surgical case reports · 2022Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most sporadic peripheral nerve sheath tumors in adults are schwannomas. These tumors usually present with significant pain but can also cause neurological deficits. Symptomatology is diverse, and successful surgical interventions demand interdisciplinarity. We retrospectively reviewed 414 patients treated between 2006 and 2017 for peripheral nerve sheath tumors. We analyzed clinical signs, symptoms, histology, and neurological function in the cohort of adult patients with schwannomas without a neurocutaneous syndrome. In 144 patients, 147 surgical interventions were performed. Mean follow-up was 3.1 years. The indication for surgery was pain (66.0%), neurological deficits (23.8%), significant tumor growth (8.8%), and suspected malignancy (1.4%). Complete tumor resection was achieved on 136/147 occasions (92.5%). The most common location of the tumors was intraspinal (49.0%), within the cervical neurovascular bundles (19.7%), and lower extremities (10.9%). Pain and neurological deficits improved significantly (
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