Evidence map›Paper›PMID 33804415›Full record

ArticleNutrients2021

Transient Effect of Infant Formula Supplementation on the Intestinal Microbiota.

Ning Chin, Gema Méndez-Lagares, Diana H Taft, Victoria Laleau, Hung Kieu, Nicole R Narayan, Susan B Roberts, David A Mills, Dennis J Hartigan-O'Connor, Valerie J Flaherman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ning ChinCalifornia National Primate Research Center, University of California, Davis, CA 95616, USA.ORCID 0000-0002-2539-3088
Gema Méndez-LagaresCalifornia National Primate Research Center, University of California, Davis, CA 95616, USA.
Diana H TaftDepartment of Food Science and Technology, University of California, Davis, CA 95616, USA.
Victoria LaleauDepartment of Pediatrics, University of California, San Francisco, CA 94143, USA.
Hung KieuCalifornia National Primate Research Center, University of California, Davis, CA 95616, USA.
Nicole R NarayanCalifornia National Primate Research Center, University of California, Davis, CA 95616, USA.
Susan B RobertsFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA.ORCID 0000-0003-1320-8460
David A MillsDepartment of Food Science and Technology, University of California, Davis, CA 95616, USA.
Dennis J Hartigan-O'ConnorCalifornia National Primate Research Center, University of California, Davis, CA 95616, USA.
Valerie J FlahermanDepartment of Pediatrics, University of California, San Francisco, CA 94143, USA.ORCID 0000-0003-3117-927X

Funding

NIH HHS AI118451NIH HHS AT008759NIH HHS HD093185UCSF Department of Pediatrics Clinical Translational Pilot Award
6 · The paper itself

Abstract

Breastfeeding is the gold standard for feeding infants because of its long-term benefits to health and development, but most infants in the United States are not exclusively breastfed in the first six months. We enrolled 24 infants who were either exclusively breastfed or supplemented with formula by the age of one month. We collected diet information, stool samples for evaluation of microbiotas by 16S rRNA sequencing, and blood samples for assessment of immune development by flow cytometry from birth to 6 months of age. We further typed the

Indexed as

Breast FeedingDietary SupplementsDiet SurveysFecesFemaleGastrointestinal MicrobiomeHumansImmune SystemInfantInfant FormulaInfant, NewbornInfant Nutritional Physiological PhenomenaMaleRNA, Ribosomal, 16SUnited StatesRNA, Ribosomal, 16Sbreastfeedingdelivery modeformula supplementationimmune developmentinfant dietmicrobiomemicrobiota–immune system interactions

Identifiers

PMID33804415
PMCPMC7998963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.