Evidence map›Paper›PMID 33804385›Full record

ArticleJournal of personalized medicine2021

PNPLA3 and SERPINA1 Variants Are Associated with Severity of Fatty Liver Disease at First Referral to a Tertiary Center.

Georg Semmler, Lorenz Balcar, Hannes Oberkofler, Stephan Zandanell, Michael Strasser, David Niederseer, Alexandra Feldman, Felix Stickel, Pavel Strnad, Christian Datz and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Georg SemmlerFirst Department of Medicine, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria.ORCID 0000-0002-0411-166X
Lorenz BalcarFirst Department of Medicine, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria.ORCID 0000-0002-6708-3061
Hannes OberkoflerDepartment of Laboratory Medicine, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria.
Stephan ZandanellFirst Department of Medicine, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria.
Michael StrasserFirst Department of Medicine, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria.
David NiederseerDepartment of Cardiology, University Heart Center Zurich, University Hospital Zurich, University of Zurich, 8006 Zurich, Switzerland.ORCID 0000-0003-3089-1222
Alexandra FeldmanFirst Department of Medicine, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria.
Felix StickelDepartment of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8006 Zurich, Switzerland.
Pavel StrnadMedical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, 52074 Aachen, Germany.ORCID 0000-0002-7122-6379
Christian DatzDepartment of Internal Medicine, General Hospital Oberndorf, Teaching Hospital of the Paracelsus Medical University Salzburg, 5110 Oberndorf, Austria.ORCID 0000-0001-7838-4532
Bernhard PaulweberFirst Department of Medicine, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria.
Elmar AignerFirst Department of Medicine, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria.
Paracelsus Medical University · ATUniversity of Zurich · CHRWTH Aachen University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single nucleotide polymorphisms (SNPs), including

Indexed as

advanced chronic liver diseaseALDcirrhosisNAFLDPNPLA3SERPINA1

Identifiers

PMID33804385
PMCPMC7999282
OpenAlexW3133915832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.