Evidence map›Paper›PMID 33804369›Full record

ReviewInternational journal of molecular sciences2021

The Cross-Talk between Mesenchymal Stem Cells and Immune Cells in Tissue Repair and Regeneration.

Carl Randall Harrell, Valentin Djonov, Vladislav Volarevic

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 106 citations in OpenAlex.

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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Carl Randall HarrellRegenerative Processing Plant, LLC, 34176 US Highway 19 N Palm Harbor, Palm Harbor, FL 34684, USA.
Valentin DjonovInstitute of Anatomy, University of Bern, Baltzerstrasse 2, 3012 Bern, Switzerland.
Vladislav VolarevicCenter for Molecular Medicine and Stem Cell Research, Department of Microbiology and Immunology, Faculty of Medical Sciences, University of Kragujevac, 69 Svetozar Markovic Street, 34000 Kragujevac, Serbia.ORCID 0000-0001-5948-9902
University of Bern · CHUniversity of Kragujevac · RS

Funding

Fakultet Medicinskih Nauka, Univerziteta U Kragujevcu MP01/18Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja ON175069 ON175103Swiss National Science Foundation IZSEZ0 185546
6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) are self-renewable, rapidly proliferating, multipotent stem cells which reside in almost all post-natal tissues. MSCs possess potent immunoregulatory properties and, in juxtacrine and paracrine manner, modulate phenotype and function of all immune cells that participate in tissue repair and regeneration. Additionally, MSCs produce various pro-angiogenic factors and promote neo-vascularization in healing tissues, contributing to their enhanced repair and regeneration. In this review article, we summarized current knowledge about molecular mechanisms that regulate the crosstalk between MSCs and immune cells in tissue repair and regeneration.

Indexed as

RegenerationWound HealingAnimalsHumansImmunomodulationLymphocytesMesenchymal Stem CellsMesenchymal Stem Cell Transplantationangiogenesisimmune cellsimmunomodulationmesenchymal stem cellsregeneration

Identifiers

PMID33804369
PMCPMC7957490
OpenAlexW3133897636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.