ArticleFoods (Basel, Switzerland)2021
Counter-Current Fractionation-Assisted Bioassay-Guided Separation of Active Compound from Blueberry and the Interaction between the Active Compound and α-Glucosidase.
Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Deciphering Pigmented Rice Varieties as Sustainable and Unexplored Valuable Sources of Bioactive Components With Health-Related Properties and Technological Applications-A Systematic Review.Comprehensive reviews in food science and food safety · 2026Pooled it
- Ultrasound-Microwave Associated Extraction of Anthocyanins From Mulberry and Their Antioxidant and Anticancer Activities.Food science & nutrition · 2025Article
- Adsorption characteristics of modified bentonites for purification of anthocyanin from saffron tepal.Food science & nutrition · 2024Article
- Carotenoid and Phenolic Compositions and Antioxidant Activity of 23 Cultivars of Corn Grain and Corn Husk Extract.Foods (Basel, Switzerland) · 2024Article
- Research Progress on the Extraction and Purification of Anthocyanins and Their Interactions with Proteins.Molecules (Basel, Switzerland) · 2024Review
- Article
- Phenolics Profile and Protective Effect on Injuried HUVEC Cells of Epicarp Extracts fromFoods (Basel, Switzerland) · 2022Article
- Bioassay-Guided Fractionation ofMolecules (Basel, Switzerland) · 2022Article
- Bioassay-guided isolation of Fenghuang Dancong tea constituents with α-glucosidase inhibition activities.Frontiers in nutrition · 2022Article
- Article
- Ultrasonic-Assisted Aqueous Two-Phase Extraction and Properties of Water-Soluble Polysaccharides fromMolecules (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
An efficient strategy for the selection of active compounds from blueberry based on counter-current fractionation and bioassay-guided separation was established in this study. Blueberry extract showed potential α-glucosidase inhibitory activity. After extraction by different solvents, the active components were enriched in water. The water extract was divided into six fractions via high-speed counter-current chromatography to further track the active components. Results indicated that the α-glucosidase inhibition rate of F4 was remarkable higher than the others. Cyanidin-3-glucoside (C3G) with a purity of 94.16% was successfully separated from F4 through column chromatography, and its structure was identified by ultraviolet spectral, Fourier-transformed infrared spectroscopy, high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.