Evidence map›Paper›PMID 33804260›Full record

ArticleDiagnostics (Basel, Switzerland)2021

HCV Diagnosis and Sequencing Using Dried Blood Spots from Patients in Kinshasa (DRC): A Tool to Achieve WHO 2030 Targets.

Teresa Carrasco, David Barquín, Adolphe Ndarabu, Mirian Fernández-Alonso, Marina Rubio-Garrido, Silvia Carlos, Benit Makonda, África Holguín, Gabriel Reina

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Teresa CarrascoMicrobiology Department, Clínica Universidad de Navarra, 31008 Pamplona, Spain.
David BarquínMicrobiology Department, Clínica Universidad de Navarra, 31008 Pamplona, Spain.
Adolphe NdarabuDepartment of Internal Medicine, Centre Hospitalier Monkole, 4484 Kinshasa, Democratic Republic of the Congo.
Mirian Fernández-AlonsoMicrobiology Department, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0001-8047-2734
Marina Rubio-GarridoHIV-1 Molecular Epidemiology Laboratory, Microbiology and Parasitology Department and Instituto Ramón y Cajal para la Investigación Sanitaria (IRYCIS), Hospital Universitario Ramón y Cajal, CIBER en Epidemiología y Salud Pública (CIBERESP), Red en Investigación Translacional en Infecciones Pediátricas (RITIP), 28034 Madrid, Spain.
Silvia CarlosISTUN, Institute of Tropical Health, Universidad de Navarra, 31008 Pamplona, Spain.
Benit MakondaDepartment of Internal Medicine, Centre Hospitalier Monkole, 4484 Kinshasa, Democratic Republic of the Congo.
África HolguínHIV-1 Molecular Epidemiology Laboratory, Microbiology and Parasitology Department and Instituto Ramón y Cajal para la Investigación Sanitaria (IRYCIS), Hospital Universitario Ramón y Cajal, CIBER en Epidemiología y Salud Pública (CIBERESP), Red en Investigación Translacional en Infecciones Pediátricas (RITIP), 28034 Madrid, Spain.ORCID 0000-0002-1330-8050
Gabriel ReinaMicrobiology Department, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0003-4079-9753
Navarre Institute of Health Research · ESClinica Universidad de Navarra · ESInstituto Ramón y Cajal de Investigación Sanitaria · ESKinshasa General Hospital · CD

Funding

Fondo de Investigación en Salud-FIS, Gobierno de España PI16/01908Gobierno de Navarra 045-2015
6 · The paper itself

Abstract

The World Health Organization has established an elimination plan for hepatitis C virus (HCV) by 2030. In Sub-Saharan Africa (SSA) access to diagnostic tools is limited, and a number of genotype 4 subtypes have been shown to be resistant to some direct-acting antivirals (DAAs). This study aims to analyze diagnostic assays for HCV based on dried blood spots (DBS) specimens collected in Kinshasa and to characterize genetic diversity of the virus within a group of mainly HIV positive patients. HCV antibody detection was performed on 107 DBS samples with Vidas

Indexed as

direct-acting antiviralsdried blood spotsgenotype 4hepatitis C virusKinshasaresistance-associated substitutions

Identifiers

PMID33804260
PMCPMC8002119
OpenAlexW3136696173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.