Evidence map›Paper›PMID 33804200›Full record

ReviewInternational journal of environmental research and public health2021

The Role of Nutritional Factors in Asthma: Challenges and Opportunities for Epidemiological Research.

Annabelle Bédard, Zhen Li, Wassila Ait-Hadad, Carlos A Camargo, Bénédicte Leynaert, Christophe Pison, Orianne Dumas, Raphaëlle Varraso

Registry-linked trialAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05728385 (Impact of Modified Specific Carbohydrate Diet on Bronchial Asthma Control in Children), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05728385 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Impact of Modified Specific Carbohydrate Diet on Bronchial Asthma Control in Children

TypeinterventionalSponsorTanta UniversityRan2023 to 2024Enrolled60ConditionsAsthma in ChildrenArmsModified Specific carbohydrate diet for 3 months
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Nutrition and growth of primary ciliary dyskinesia patients: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
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  6. Association between asthma, obesity, and metabolic syndrome in adolescents and young adults.The Journal of asthma : official journal of the Association for the Care of Asthma · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
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  15. Review
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  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Annabelle BédardUniversité Paris-Saclay, UVSQ, University Paris-Sud, Inserm, Équipe d'Épidémiologie Respiratoire Intégrative, CESP, 94807 Villejuif, France.ORCID 0000-0002-7842-8889
Zhen LiClinical Research Centre, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 200092, China.ORCID 0000-0002-6443-8963
Wassila Ait-HadadUniversité Paris-Saclay, UVSQ, University Paris-Sud, Inserm, Équipe d'Épidémiologie Respiratoire Intégrative, CESP, 94807 Villejuif, France.
Carlos A CamargoDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-5071-7654
Bénédicte LeynaertUniversité Paris-Saclay, UVSQ, University Paris-Sud, Inserm, Équipe d'Épidémiologie Respiratoire Intégrative, CESP, 94807 Villejuif, France.ORCID 0000-0001-5045-2492
Christophe PisonService Hospitalier Universitaire Pneumologie, Pôle Thorax et Vaisseaux, CHU Grenoble Alpes, Laboratoire de Bioénergétique Fondamentale et Appliquée, Inserm 1055, Université Grenoble Alpes, 38400 Grenoble, France.
Orianne DumasUniversité Paris-Saclay, UVSQ, University Paris-Sud, Inserm, Équipe d'Épidémiologie Respiratoire Intégrative, CESP, 94807 Villejuif, France.ORCID 0000-0001-8423-2826
Raphaëlle VarrasoUniversité Paris-Saclay, UVSQ, University Paris-Sud, Inserm, Équipe d'Épidémiologie Respiratoire Intégrative, CESP, 94807 Villejuif, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of asthma has nearly doubled over the last decades. Twentieth century changes in environmental and lifestyle factors, including changes in dietary habits, physical activity and the obesity epidemic, have been suggested to play a role in the increase of asthma prevalence and uncontrolled asthma worldwide. A large body of evidence has suggested that obesity is a likely risk factor for asthma, but mechanisms are still unclear. Regarding diet and physical activity, the literature remains inconclusive. Although the investigation of nutritional factors as a whole (i.e., the "diet, physical activity and body composition" triad) is highly relevant in terms of understanding underlying mechanisms, as well as designing effective public health interventions, their combined effects across the life course has not received a lot of attention. In this review, we discuss the state of the art regarding the role of nutritional factors in asthma, for each window of exposure. We focus on the methodological and conceptual challenges encountered in the investigation of the complex time-dependent interrelations between nutritional factors and asthma and its control, and their interaction with other determinants of asthma. Lastly, we provide guidance on how to address these challenges, as well as suggestions for future research.

Indexed as

AsthmaLife StyleDietExerciseHumansObesityasthmaasthma controlbody compositiondietnutritional factorsphysical activity

Identifiers

PMID33804200
PMCPMC7999662

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.